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A1340000

Atenolol

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

(±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide

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About This Item

Fórmula empírica (notación de Hill):
C14H22N2O3
Número de CAS:
29122-68-7
Peso molecular:
266.34
Número CE:
249-451-7
Número MDL:
MFCD00057645
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329770360
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

atenolol

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CC(C)NCC(O)COc1ccc(CC(N)=O)cc1

InChI

1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)

Clave InChI

METKIMKYRPQLGS-UHFFFAOYSA-N

Información sobre el gen

human ... ADRB1(153)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Atenolol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

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Atenolol, United States Pharmacopeia (USP) Reference Standard

Y0001089

Atenolol for system suitability, European Pharmacopoeia (EP) Reference Standard

PHR1909

Atenolol, Pharmaceutical Secondary Standard; Certified Reference Material

BP370

Atenolol impurity standard, British Pharmacopoeia (BP) Reference Standard

BP492

Atenolol, British Pharmacopoeia (BP) Reference Standard

1044367

Atenolol Related Compound F, United States Pharmacopeia (USP) Reference Standard

1044265

Atenolol Related Compound B, United States Pharmacopeia (USP) Reference Standard

1044254

Atenolol Related Compound A, United States Pharmacopeia (USP) Reference Standard

1044276

Atenolol Related Compound C, United States Pharmacopeia (USP) Reference Standard

1044298

Atenolol Related Compound E, United States Pharmacopeia (USP) Reference Standard

1044287

Atenolol Related Compound D, United States Pharmacopeia (USP) Reference Standard

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Sripal Bangalore et al.
The American journal of medicine, 127(10), 939-953 (2014-06-15)
Debate exists about the efficacy of β-blockers in myocardial infarction and their required duration of usage in contemporary practice. We conducted a MEDLINE/EMBASE/CENTRAL search for randomized trials evaluating β-blockers in myocardial infarction enrolling at least 100 patients. The primary outcome
Ronald V Lacro et al.
The New England journal of medicine, 371(22), 2061-2071 (2014-11-19)
Aortic-root dissection is the leading cause of death in Marfan's syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers. We conducted a randomized trial comparing
Atenolol: pharmacokinetic/dynamic aspects of comparative developmental toxicity.
Sonia A Tabacova et al.
Reproductive toxicology (Elmsford, N.Y.), 16(1), 1-7 (2002-04-06)
H Sakurai et al.
Japanese circulation journal, 64(11), 893-896 (2000-12-08)
Cardiogenic shock developed in a 72-year-old Japanese woman during combination therapy with verapamil and atenolol for recurrent supraventricular arrhythmia. She had coronary atherosclerosis, liver cirrhosis and bradycardia-tachycardia syndrome. Despite of the high-dose catecholamines and counterpulsation, she progressively deteriorated. Bolus administration
Laura M Kuyper et al.
The Canadian journal of cardiology, 30(5 Suppl), S47-S53 (2014-04-23)
Previous reviews have shown that β-blocker use for the treatment of hypertension without compelling indications was associated with increased risk of stroke in the elderly. It remains unclear whether this increased risk was driven by the type of β-blocker. We
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