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60372

Sigma-Aldrich

Secoisolariciresinol

≥95.0% (HPLC)

Sinónimos:

(2R,3R)-2,3-Bis(4-hydroxy-3-methoxybenzyl)-1,4-butanediol

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About This Item

Fórmula empírica (notación de Hill):
C20H26O6
Peso molecular:
362.42
Beilstein:
6611290
Número CE:
249-599-2
Número MDL:
MFCD01075136
Código UNSPSC:
41116105
ID de la sustancia en PubChem:
329758917
NACRES:
NA.21

Nivel de calidad

100

Ensayo

≥95.0% (HPLC)

Formulario

solid

cadena SMILES

OC[C@@H]([C@H](CO)CC1=CC=C(O)C(OC)=C1)CC2=CC(OC)=C(O)C=C2

InChI

1S/C20H26O6/c1-25-19-9-13(3-5-17(19)23)7-15(11-21)16(12-22)8-14-4-6-18(24)20(10-14)26-2/h3-6,9-10,15-16,21-24H,7-8,11-12H2,1-2H3/t15-,16-/m0/s1

Clave InChI

PUETUDUXMCLALY-HOTGVXAUSA-N

Aplicación

Secoisolariciresinol is a metabolite of secoisolariciresinol diglucoside (SDG), an antioxidant present in flaxseed.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Forma física

mixture of enantiomers of the (R*,R*)-diastereoisomer

Otras notas

Component of functional food. Flaxseed lignan with antioxidant activity

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCH0033
BCCB5794
BCBR1232V

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(+)-Pinoresinol phyproof® Reference Substance

PHL89525

(+)-Pinoresinol

Eudesmine ≥95% (LC/MS-ELSD)

Sigma-Aldrich

SMB00182

Eudesmine

(−)-Arctigenin ≥95% (LC/MS-ELSD)

Sigma-Aldrich

SMB00075

(−)-Arctigenin

(−)-Syringaresinol 4-O-β-D-glucoside phyproof® Reference Substance

PHL83914

(−)-Syringaresinol 4-O-β-D-glucoside

Hisashi Nishiwaki et al.
Bioscience, biotechnology, and biochemistry, 75(9), 1735-1739 (2011-09-08)
The larvicidal activity against Culex pipiens of all stereoisomers of dihydroguaiaretic acid (DGA) and secoisolariciresinol was measured, and these DGAs were found to be potent. Sixteen (-)-DGA derivatives were then newly synthesized to analyze their structure-activity relationship. Two derivatives monohydroxylated
Carol J Fabian et al.
Cancer prevention research (Philadelphia, Pa.), 3(10), 1342-1350 (2010-08-21)
Preclinical and correlative studies suggest reduced breast cancer with higher lignan intake or blood levels. We conducted a pilot study of modulation of risk biomarkers for breast cancer in premenopausal women after administration of the plant lignan secoisolariciresinol given as
Shiori Tominaga et al.
Food & function, 3(1), 76-82 (2011-10-28)
Flaxseed lignan, secoisolariciresinol has been reported to possess health benefits. We previously synthesized each stereoisomer of secoisolariciresinol and found that (-)-secoisolariciresinol reduces lipid accumulation and induces adiponectin production in 3T3-L1 adipocytes. Here we show the effects of (-)-secoisolariciresinol on high-fat
Niina M Saarinen et al.
The British journal of nutrition, 104(6), 833-841 (2010-04-15)
Limited information is available on lignan metabolism and tissue distribution between sexes and the effects of prolonged lignan exposure on tissue concentrations. In the present study, excretion and tissue distribution of lignans were compared after 1 d and 7 d
K Struijs et al.
Journal of applied microbiology, 107(1), 308-317 (2009-03-24)
It has been investigated whether secoisolariciresinol (SECO) and anhydrosecoisolariciresinol (AHS), an acid degradation product of SECO, could be fermented in a similar way, and to a similar extent, by members of the intestinal microbiota. AHS and SECO were demethylated by
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