ABF218

Anti-STIM2 Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Stromal interaction molecule 2, STIM2
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: human, mouse
• técnicas: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• Nº de acceso UniProt: Q9P246
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... STIM2(57620)

Descripción

Descripción general

Stromal interaction molecule 2 (STIM2) plays an important role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. It inhibits STIM1-mediated store-operated Ca++ entry; however, STIM2 can form complexes with STIM1. This suggests that STIM1 and STIM2 may play a coordinated role in controlling Ca++ entry. STIM2 is expressed in all tissues and tumor cell lines examined.

Especificidad

This antibody recognizes the intermediate domain of STIM2.

Inmunógeno

Epitope: Intermediate domain

KLH-conjugated linear peptide corresponding to the intermediate domain of human STIM2.

Aplicación

Detect Stromal interaction molecule 2 using this rabbit polyclonal antibody, Anti-STIM2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected STIM2 in human spleen tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected STIM2 in human spleen cells.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Calidad

Evaluated by Western Blotting in A-20 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected STIM2 in 15 µg of A-20 cell lysate.

Descripción de destino

~98 kDa observed

Forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
A-20 cell lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable