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AB9328

Sigma-Aldrich

Anti-Thioredoxin 1 Antibody

serum, Chemicon®

Sinónimos:

TRX1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat

species reactivity (predicted by homology)

human (sequence homology 14/15)

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_005933.2
NM_024891.1

UniProt accession no.

Q6P902

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TXN(7295)

Specificity

Recognizes Thioredoxin 1 (TRX1).

Immunogen

Synthetic peptide from rat/mouse Thioredoxin 1.

Application

Detect Thioredoxin 1 using this Anti-Thioredoxin 1 Antibody validated for use in WB.
Immunoblotting: 1:1,000-1:5,000 using ECL. Reacts with the ~12-14 kD thioredoxin 1 protein. Additional bands >30 kD may been seen.

Suggested dilution and blocking buffer is TBST containing 5% non-fat milk. Suggested gel percentage is 15%. Suggested incubation time is overnight.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

Linkage

Replaces: MABN1090

Physical form

Rabbit serum. Liquid. Contains no preservative.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Xiaoqin Zhao et al.
Acta biochimica et biophysica Sinica, 46(4), 318-329 (2014-03-01)
Cardiac complications are the leading cause of death in diabetes. However, the mechanism of diabetes in inducing myocardial injury and apoptosis, and whether the thioredoxin (Trx) system is involved remain unclear. In this study, male Sprague-Dawley rats were randomly divided
Chiara Milanese et al.
Nature communications, 10(1), 4887-4887 (2019-10-28)
Accumulation of DNA lesions causing transcription stress is associated with natural and accelerated aging and culminates with profound metabolic alterations. Our understanding of the mechanisms governing metabolic redesign upon genomic instability, however, is highly rudimentary. Using Ercc1-defective mice and Xpg

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