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AB1690

Sigma-Aldrich

Anti-Ubiquitin Antibody

serum, Chemicon®

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

bovine, eukaryotes, human

fabricante / nombre comercial

Chemicon®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... UBAP2(55833)

Especificidad

Ubiquitin (76 amino acid, 8.5 kDa). Shows staining of neurofibrillary tangles, neurites in senile plaques and a subset of neuronal processes. No reactivity seen to tau, neurofilament or microtubule-associated proteins.

Inmunógeno

Purified uboquitin covalently coupled to KLH using glutaraldehde.

Aplicación

Anti-Ubiquitin Antibody detects level of Ubiquitin & has been published & validated for use in WB, IH, IH(P).
Immunohistochemistry: 1:1,000-1:5,000. Tissue fixed in 10% formalin, Bouin′s fixative for 1-2 days and embedded in paraffin, or unfixed frozen tissues may be used.

Immunoblotting: 1:1,000-1:5,000.

Optimal working dilutions must be determined by end user.
Research Category
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism

Forma física

Neat rabbit antisera with 10 mM sodium azide.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1


Certificados de análisis (COA)

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Jackalina M Van Kampen
Methods in molecular biology (Clifton, N.J.), 1806, 255-267 (2018-06-30)
Progranulin (PGRN) is a multifunctional protein that is widely expressed throughout the brain, where it has been shown to be a critical regulator of CNS inflammation (Ahmed et al., J Neuroinflammation 4:7, 2007; Yin et al., J Exp Med 207:117-128
Nataša Bauer et al.
Frontiers in plant science, 10, 1469-1469 (2019-12-12)
MATH-BTB proteins are known to act as substrate-specific adaptors of CUL3-based E3 ligases in the ubiquitin proteasome pathway. Their BTB domain binds to CUL3 scaffold proteins and the less conserved MATH domain targets a highly diverse collection of substrate proteins
Evaluation of selected binding domains for the analysis of ubiquitinated proteomes.
Nakayasu, ES; Ansong, C; Brown, JN; Yang, F; Lopez-Ferrer, D; Qian, WJ; Smith, RD; Adkins, JN
Journal of the American Society For Mass Spectrometry null
Peter Sutovsky et al.
Reproduction (Cambridge, England), 129(3), 269-282 (2005-03-08)
Major vault protein (MVP), also called lung resistance-related protein is a ribonucleoprotein comprising a major part (>70%) of the vault particle. The function of vault particle is not known, although it appears to be involved in multi-drug resistance and cellular
Tshianda N M Alerte et al.
Neuroscience letters, 435(1), 24-29 (2008-03-04)
Tyrosine hydroxylase (TH), the rate limiting enzyme in catecholamine synthesis, is frequently used as a marker of dopaminergic neuronal loss in animal models of Parkinson's disease (PD). We have been exploring the normal function of the PD-related protein alpha-synuclein (alpha-Syn)

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