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Key Documents

1.52320

Supelco

Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns

L × I.D. 25 mm × 2 mm HPLC Column

Sinónimos:

Chromolith® HighResolution RP-18 endcapped 25-2 HPLC column

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About This Item

UNSPSC Code:
41115709
NACRES:
SB.52

product name

Chromolith® HighResolution RP-18 desactivada, L × I.D. 25 mm × 2 mm HPLC column

Quality Level

feature

endcapped

extent of labeling

18% Carbon loading

parameter

200 bar pressure
50 °C max. temp.

technique(s)

HPLC: suitable
mass spectrometry (MS): suitable (High)

column L × I.D.

25 mm × 2 mm

matrix

highly porous
monolithic silica

matrix active group

C18 bonding phase, octadecylsilane (ODS)

pore size

1.5 μm macroporosity
15 nm mesoporosity

operating pH range

2-7.5

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General description

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® HighResolution RP-18 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octadecylsilane with full end-capping. Chromolith® HighResolution RP-18 endcapped columns fall under the USP L1 Classification. The column efficiency is comparable to a 2.7 to 3 μm particle size fully porous particulate column.
The column dimension of 25 mm length and 2 mm I.D. is the best choice for very rapid separations meeting UHPLC and LC-MS needs.

Chromolith® HighResolution RP-18 endcapped columns with 2 mm internal diameter are ideal for use with UHPLC or UPLC instruments, thanks to their very small internal volumes. A particular benefit is very fast analysis, reduced sample-preparation and the low column backpressure. Ultra-high performance and extremely low operating pressure make Chromolith® 2 mm I.D. columns truly unique. Chromolith® and Chromolith® HighResolution columns are perfectly suitable for LC-MS use; however, the column dimension of 2 mm I.D. or below is preferred to be used in LC-MS methods.

The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes
—Connection of columns, flow gradients and the use of mobile phases with higher viscosity

The recommended Guard-columns are:
Chromolith® HighResolution RP-18 endcapped 5-2 guard cartridges (3 pieces) [1.52325] with the Chromolith® Guard Cartridge Holder 5 mm x 2 mm [1.52355]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

Flyer: UHPLC-like performance - Rapid and Robust at Low Pressure - Chromolith® HighResolution RP-18 endcapped 2 mm I.D. HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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