14-331-M
SGK1 (δ1-59, S422D) Protein, active, 6 µg
Active, N-truncated (missing N-terminal 60 amino acids), His-tagged, human SGK1 fusion protein, containing a S422D mutation, for use in Kinase Assays.
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
Productos recomendados
biological source
human
Quality Level
100
300
mol wt
Mw 48 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
Gene Information
human ... SGK1(6446)
General description
N-truncated (missing Nterminal 60 amino acids), His-tagged, human SGK1 fusion protein, containing a S422D mutation
Product Source: expressed in Sf21 cells
Biochem/physiol Actions
Protein Target: SGK1
Target Sub-Family: AGC
Quality
routinely evaluated by Kinase assay
Physical form
Ni-NTA agarose
Storage and Stability
1 year at -70°C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1
Wang, Dongsheng, et al
American Journal of Physiology. Cell Physiology, 289, C802-C810 (2005)
Dana Yoo et al.
The Journal of biological chemistry, 278(25), 23066-23075 (2003-04-10)
The Kir1.1 (ROMK) subtypes of inward rectifier K+ channels mediate potassium secretion and regulate sodium chloride reabsorption in the kidney. The density of ROMK channels on the cortical collecting duct apical membrane is exquisitely regulated in concert with physiological demands.
T Kobayashi et al.
The Biochemical journal, 344 Pt 1, 189-197 (1999-11-05)
The catalytic domain of serum- and glucocorticoid-induced protein kinase (SGK) is 54% identical with protein kinase B (PKB) and, like PKB, is activated in vitro by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and in vivo in response to signals that activate phosphatidylinositol
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico