Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

05-882

Sigma-Aldrich

Anti-Parkin Antibody, clone PRK8

ascites fluid, clone PRK8, Upstate®

Sinónimos:

Anti-AR-JP, Anti-LPRS2, Anti-PARK2, Anti-PDJ

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

PRK8, monoclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NM_004562

UniProt accession no.

O60260

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... PARK2(5071)

Specificity

Parkin

Immunogen

Full length recombinant human Parkin. Epitope has been mapped to the second ring domain (aa 399-465)

Application

Anti-Parkin Antibody, clone PRK8 detects level of Parkin & has been published & validated for use in IP, WB, IC, IH.

Quality

routinely evaluated by immunoblot on RIPA lysates from HEK293 cells

Target description

52kDa May be observed as a doublet at 52 and 46kDa

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Nobutaka Hattori et al.
Lancet (London, England), 364(9435), 722-724 (2004-08-25)
The cause and pathogenesis of Parkinson's disease remain unknown; mitochondrial dysfunction, oxidative damage, environmental factors, and genetic predisposition might all be involved. Identification of the causative genes for familial Parkinson's diseases allow study of the pathogenesis of the disease at
Genotype-phenotype correlation: familial Parkinson disease.
Mori, Hideo, et al.
Neuropathology : Official Journal of the Japanese Society of Neuropathology, 23, 90-94 (2003)
Keiji Tanaka et al.
Biochimica et biophysica acta, 1695(1-3), 235-247 (2004-12-02)
The ubiquitin-proteasome system (UPS) is important for intracellular proteolysis, and is responsible for a diverse array of biologically important cellular processes, such as cell-cycle progression, signaling cascades and developmental programs. This system is also involved in the protein quality control
Molecular pathways of neurodegeneration in Parkinson's disease.
Dawson, Ted M and Dawson, Valina L
Science (New York, N.Y.), 302, 819-822 (2003)
Are ubiquitination pathways central to Parkinson's disease?
Giasson, Benoit I and Lee, Virginia M-Y
Cell, 114, 1-8 (2003)
Ver todos los artículos relacionados

Artículos

Autophagy Mitophagy in Tumor Cell Survival Death

Autophagy is a regulated process involved in cell growth, development, and recycling of cytoplasmic components in cells.

Autophagy Mitophagy in Tumor Cell Survival Death

Autophagy is a regulated process involved in cell growth, development, and recycling of cytoplasmic components in cells.

Autophagy Mitophagy in Tumor Cell Survival Death

Autophagy is a regulated process involved in cell growth, development, and recycling of cytoplasmic components in cells.

Autophagy Mitophagy in Tumor Cell Survival Death

Autophagy is a regulated process involved in cell growth, development, and recycling of cytoplasmic components in cells.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico