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Merck

D-015

Supelco

Diphenhydramine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C17H22ClNO
Número de CAS:
Peso molecular:
291.82
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl

InChI

1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

InChI key

PCHPORCSPXIHLZ-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

General description

Diphenhydramine is an antihistamine sold over the counter under the trade name Benadryl® and in other over the counter medications such as Tylenol PM, Advil PM, and Excedrin PM. Dihydramine is also consumed recreationally as a euphoriant and a deliriant.

Application


  • Hepatoprotective effects of polyphenols: Studies on the hepatoprotective effects of polyphenol-enriched fractions against oxidative stress in Acetaminophen-induced liver injury incorporate the analysis of Acetaminophen Related Compound D. This research underscores its relevance in pharmacology and toxicology, providing a deeper understanding of drug-induced liver injuries and potential therapeutic approaches (Wu et al., 2017).


Legal Information

Benadryl is a registered trademark of Johnson & Johnson
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Benjamin W Friedman et al.
Annals of emergency medicine, 62(4), 311-318 (2013-04-10)
We compare metoclopramide 20 mg intravenously, combined with diphenhydramine 25 mg intravenously, with ketorolac 30 mg intravenously in adults with tension-type headache and all nonmigraine, noncluster recurrent headaches. In this emergency department (ED)-based randomized, double-blind study, we enrolled adults with
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Pruritus, the sensation of itch, which evokes reflex scratching behavior, has a diverse etiology. Because of its clinical significance, mechanisms of pruriception are an important topic. In the present work we describe and validate a paw motion detector (PMD) system.
Paige M Evans et al.
American journal of veterinary research, 73(12), 1983-1986 (2012-11-28)
To evaluate the effects of oral administration of diphenhydramine on pupil diameter, intraocular pressure (IOP), tear production, tear film quality, corneal sensitivity, and conjunctival goblet cell density (GCD) in clinically normal adult dogs. 12 healthy adult dogs. All dogs received

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