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B-034

Supelco

Bupropion hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C13H19Cl2NO
Número de CAS:
31677-93-7
Peso molecular:
276.20
EC Number:
200-659-6
MDL number:
MFCD00055209
UNSPSC Code:
41116107
PubChem Substance ID:
329773108
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

Cl.CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1

InChI

1S/C13H18ClNO.ClH/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10;/h5-9,15H,1-4H3;1H

InChI key

HEYVINCGKDONRU-UHFFFAOYSA-N

Gene Information

human ... SLC6A2(6530) , SLC6A3(6531)

Categorías relacionadas

General description

A certified solution standard suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to urine drug testing and pharmaceutical research. Bupropion is an antidepressant and smoking cessation drug sold under the trade names Wellbutrin® and Zyban®.

Application


  • Investigation of neurotoxic effects: Research on propofol′s potential neurotoxic impact on the hippocampus has deepened understanding of its effects on mitochondrial function. (Ebrahimi et al., 2024).

  • Enhancement of cardiopulmonary bypass outcomes: Propofol is used in clinical trials to explore its efficacy in reducing biomarkers of organ injury during cardiac surgery. (Smartt et al., 2024).

  • Development of nanoencapsulation techniques: Propofol is being researched for its encapsulation in nanocarriers to improve its delivery efficiency and reduce side effects. Such innovations in drug delivery are aimed at enhancing the pharmacological profile of anesthetics, making them safer and more effective (Abdoullateef et al., 2024).


Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Wellbutrin is a registered trademark of GlaxoSmithKline LLC
Zyban is a registered trademark of Everris International B.V.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Leonie S Brose et al.
Mayo Clinic proceedings, 88(3), 226-233 (2013-03-16)
To compare the effectiveness of varenicline and combination nicotine replacement therapy (NRT) for treating smokers attempting to stop, as it is unclear which of the 2 is more effective. Data from 167,487 treatment episodes in patients from 42 National Health
Ian A Cook et al.
The Journal of clinical psychiatry, 74(1), 51-56 (2013-02-20)
Clinical trials in major depressive disorder (MDD) commonly assess remission at a single endpoint. Complementary, clinically relevant metrics include the likelihood and speed of achieving sustained remission. A neurophysiologic measure, the Antidepressant Treatment Response (ATR) index, previously predicted 8-week outcomes
Frank T Leone et al.
Chest, 143(5 Suppl), e61S-e77S (2013-05-10)
Continued tobacco use in the setting of lung cancer management is frequently confounding and always of critical importance. We summarized the published literature concerning the management of tobacco dependence in patients with lung cancer and offer recommendations for integrating dependence
P L Bölcskei et al.
Deutsche medizinische Wochenschrift (1946), 138(17), 902-907 (2013-04-18)
Smoking causes about 5 Million deaths worldwide every year. Prevention and cessation of smoking should therefore be one of the most important public health priorities. The family doctor as a trusted contact and representative of the health care system plays
Danielle Baribeau et al.
Journal of addiction medicine, 7(3), 216-217 (2013-03-23)
Bupropion is an antidepressant commonly prescribed as a smoking cessation aid. It has effects on dopamine and norepinephrine, and can lower seizure threshold, particularly in overdose. Several cases of recreational use of bupropion via nasal insufflation have been reported in
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