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Merck
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Key Documents

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924490

Sigma-Aldrich

Hyaluronic acid methacrylate

Low Viscosity, Low Endotoxin, 0.2 um sterile filtered, 0.2 μm, sterile-filtered

Sinónimos:

HAMA, Hyaluronan, Hyaluronic acid, MeHA

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About This Item

Fórmula lineal:
(NaC20H28NO15)n
UNSPSC Code:
12352106
NACRES:
NA.23

Quality Level

100

description

Validation : HNMR at 40°C

sterility

sterile-filtered

form

(Solid chunks, fibers or powder)

impurities

≤10 CFU/g Bioburden (Fungal)
≤10 CFU/g Bioburden (Total Aerobic)
100 EU/g Endotoxin

color

white to pale yellow

particle size

0.2 μm

storage temp.

2-8°C

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Application

Hyaluronic acid (HA) is a linear polysaccharide of alternating D-glucuronic acid and N-acetyl-D-glucosamine found primarily in connective tissues. HA based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug deliery applications. The methacrylate functionalized hyaluronic acid is photo-crosslinkable, and can be used to generate crosslinked hydrogels.

Packaging

1EA = 500 mg of lyophilized material in glass bottle.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Stiffness and adhesivity control aortic valve interstitial cell behavior within hyaluronic acid based hydrogels.
Duan, et al.
Acta Biomaterialia, 9, 7640-7650 (2018)
Photocrosslinkable Hyaluronan-Gelatin Hydrogels for Two-Step Bioprinting
Skardal, et al.
Tissue Engineering: Part A, 16 (8) (2010)
Micromolding of shape-controlled, harvestable cell-laden hydrogels.
Yeh, et al.
Biomaterials, 27, 5391-5398 (2007)
Influence of Three-Dimensional Hyaluronic Acid Microenvironments on Mesenchymal Stem Cell Chondrogenesis
Chung and Burdick
Tissue Engineering: Part A, 15(2) (2009)
Bin Duan et al.
Acta biomaterialia, 9(8), 7640-7650 (2013-05-08)
Bioactive and biodegradable hydrogels that mimic the extracellular matrix and regulate valve interstitial cells (VIC) behavior are of great interest as three-dimensional (3-D) model systems for understanding mechanisms of valvular heart disease pathogenesis in vitro and the basis for regenerative
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