901702

Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone)

PEG average M_n 5000, PCL average M_n 5000

• Sinónimos: Carboxylic acid PEG-PCL diblock copolymer, Carboxylic acid-PEG-PCL, PEG-b-PCL, PEG-PCL
• Fórmula lineal: C₆H₁₁O₃S[C₂H₄O]n[C₆H₁₀O₂]mH
• Código UNSPSC: 12352106
• NACRES: NA.23

Propiedades

• Formulario: powder or solid
• mol peso: PCL average M_n 5000; PEG average M_n 5000
• color: white to off-white
• PDI: ≤1.3 (by GPC)
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C

Descripción

Aplicación

Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable