89231
(−)-α-Thujone
≥96.0% (GC)
Sinónimos:
(-)-alpha-Thujone, (1S,4R)-1-Isopropyl-4-methylbicyclo[3.1.0]hexan-3-one
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About This Item
Fórmula empírica (notación de Hill):
C10H16O
Peso molecular:
152.23
Beilstein:
4660369
Número CE:
Número MDL:
Código UNSPSC:
12352115
ID de la sustancia en PubChem:
NACRES:
NA.22
Productos recomendados
Nivel de calidad
Ensayo
≥96.0% (GC)
Formulario
liquid
actividad óptica
[α]20/D −19.0±2.0°, neat
índice de refracción
n20/D 1.450
densidad
0.914 g/mL at 20 °C (lit.)
grupo funcional
ketone
temp. de almacenamiento
2-8°C
cadena SMILES
CC(C)[C@@]12C[C@@H]1[C@@H](C)C(=O)C2
InChI
1S/C10H16O/c1-6(2)10-4-8(10)7(3)9(11)5-10/h6-8H,4-5H2,1-3H3/t7-,8-,10+/m1/s1
Clave InChI
USMNOWBWPHYOEA-MRTMQBJTSA-N
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Descripción general
(-)-α-Thujone, a monoterpene ketone found in the essential oil of Thuja occidentalis, shows potent antitumorigenic effect.
Aplicación
- A six-step total synthesis of α-thujone and d6-α-thujone, enabling facile access to isotopically labelled metabolites: This study presents a concise method for synthesizing α-thujone, useful for creating isotopically labeled derivatives for research purposes (Thamm et al., 2016).
- Enhancement of CD3AK cell proliferation and killing ability by α-thujone: Investigates α-thujone′s ability to enhance the proliferation and cytotoxic activity of CD3AK cells, suggesting potential immunological applications (Zhou et al., 2016).
- α-Thujone exhibits an antifungal activity against F. graminearum by inducing oxidative stress, apoptosis, epigenetics alterations and reduced toxin synthesis: Demonstrates the antifungal effects of α-thujone against Fusarium graminearum, which could make it a valuable alternative to traditional fungicides (Teker et al., 2021).
Acciones bioquímicas o fisiológicas
GABAA receptor antagonist.
Otras notas
Chiral building block
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 4 Oral
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
147.2 °F - closed cup
Punto de inflamabilidad (°C)
64 °C - closed cup
Equipo de protección personal
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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