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Merck

756822

Sigma-Aldrich

Óxido de deuterio

filtered, 99.8 atom % D

Sinónimos:

Agua pesada, Agua-d2

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About This Item

Fórmula empírica (notación de Hill):
D2O
Número de CAS:
Peso molecular:
20.03
Número CE:
Número MDL:
Código UNSPSC:
12352303
ID de la sustancia en PubChem:
NACRES:
NA.12

Nivel de calidad

pureza isotópica

99.8 atom % D

Formulario

liquid

técnicas

HPLC: suitable
bio NMR: suitable
protein expression: suitable

bp

101.4 °C (lit.)

mp

3.8 °C (lit.)

densidad

1.107 g/mL at 25 °C

aplicaciones

pharmaceutical

temp. de almacenamiento

room temp

cadena SMILES

[2H]O[2H]

InChI

1S/H2O/h1H2/i/hD2

Clave InChI

XLYOFNOQVPJJNP-ZSJDYOACSA-N

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Descripción general

Deuterium oxide (D2O) is also known as heavy water. It is the deuterated form of water, as both the protons in H2O have been replaced with a deuterium isotope.

Aplicación

D2O can be used as a solvent in:      
  • High-resolution NMR (Nuclear magnetic resonance)      
  • FTIR (Fourier-transform infrared)      
  • Bio NMR studies      
  • Polarized visible Raman spectroscopic studies      
  • Protein expression

D2O is also used to prepare deuterium-labeled compounds in various fields such as pharmaceutical, bioanalytical, biological, and environmental chemistry via H-D exchange reactions to study drug metabolism mechanisms, reaction mechanisms, and the structure of biomolecules, and residual agrochemicals in foods using suitable analytical methods.

Envase

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Los clientes también vieron

R Schweitzer-Stenner et al.
Journal of the American Chemical Society, 123(39), 9628-9633 (2001-09-27)
We have measured the polarized visible Raman and FTIR spectra of trialanine and triglycine in D(2)O at acid, neutral, and alkaline pD. From the Raman spectra we obtained the isotropic and the anisotropic scattering. A self-consistent spectral analysis of the
Raphael Böhm et al.
Structure (London, England : 1993), 28(2), 206-214 (2019-12-22)
The voltage-dependent anion channel (VDAC) forms the primary diffusion pore of the outer mitochondrial membrane. In its apo form, VDAC adopts an open conformation with high conductance. States of lower conductance can be induced by ligand binding or the application
Liset Westera et al.
Blood, 122(13), 2205-2212 (2013-08-16)
Quantitative knowledge of the turnover of different leukocyte populations is a key to our understanding of immune function in health and disease. Much progress has been made thanks to the introduction of stable isotope labeling, the state-of-the-art technique for in
Takhar Kasumov et al.
American journal of physiology. Heart and circulatory physiology, 304(9), H1201-H1214 (2013-03-05)
Traditional proteomics provides static assessment of protein content, but not synthetic rates. Recently, proteome dynamics with heavy water ((2)H2O) was introduced, where (2)H labels amino acids that are incorporated into proteins, and the synthesis rate of individual proteins is calculated
Lars Holm et al.
American journal of physiology. Endocrinology and metabolism, 304(8), E895-E907 (2013-02-21)
A method to determine the rate of protein breakdown in individual proteins was developed and tested in rats and confirmed in humans, using administration of deuterium oxide and incorporation of the deuterium into alanine that was subsequently incorporated into body

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