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Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 20,000, methoxy, hydroxyl

Sinónimos:

Polyethylene glycol monomethyl ether

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About This Item

Fórmula lineal:
CH3(OCH2CH2)nOH
Número de CAS:
9004-74-4
Número MDL:
MFCD00084416
Código UNSPSC:
12162002
NACRES:
NA.23

Nombre del producto

Poly(ethylene glycol) methyl ether, average Mn 20,000

densidad de vapor

>1 (vs air)

Nivel de calidad

100

presión de vapor

0.05 mmHg ( 20 °C)

Formulario

powder or crystals

mol peso

average Mn 20,000

mp

64-69 °C

Mw/Mn

≤1.2

Ω-final

hydroxyl

α-final

methoxy

temp. de almacenamiento

−20°C

cadena SMILES

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

Clave InChI

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Aplicación

  • Deoxycholic acid-grafted PEGylated chitosan micelles for the delivery of mitomycin C.: This study develops PEGylated chitosan micelles grafted with deoxycholic acid for effective delivery of mitomycin C, showcasing the potential of PEGylated compounds in pharmaceutical formulations and drug delivery systems (Zhang et al., 2015).

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

359.6 °F

Punto de inflamabilidad (°C)

182 °C

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Certificados de análisis (COA)

Lot/Batch Number
MKCQ4514
MKCM1673
MKCL2175
MKCK9517
MKCH9258

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Hyo Won Seo et al.
Biomaterials, 34(11), 2748-2757 (2013-01-25)
The effectiveness of systemically administered anticancer treatments is limited by difficulties in achieving therapeutic doses within tumors, a problem that is complicated by dose-limiting side effects to normal tissue. To increase the efficacy and reduce the toxicity of systemically administered
Pengxiang Zhao et al.
Chemical communications (Cambridge, England), 49(31), 3218-3220 (2013-03-14)
"Click" chemistry now offers access to a great variety of triazoles, and the first example of a strategy to stabilize gold nanoparticles (AuNPs) with a new 1,2,3-triazole-mPEG ligand is developed here together with preliminary examples of possible applications.
Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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