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664049

Sigma-Aldrich

PAMAM Dendrimer Kit, generations 4-7

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About This Item

UNSPSC Code:
12162002
eCl@ss:
32161000
NACRES:
NA.23

description

amino surface groups

feature

core type ethylenediamine core (2-carbon core)

storage temp.

2-8°C

General description

Ethylenediamine-core poly(amidoamine) (PAMAM) dendrimers are highly branched, “tree-like” core-shell nanostructures made up of amide and amine functional subunits.

Application

PAMAM Dendrimer Kit, generations 4-7 can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers, allowing to mix otherwise immiscible materials.

Packaging

unit weight includes solvent

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • 412449PAMAM dendrimer, ethylenediamine core, generation 4.0 solution, 10 wt. % in methanol 1 gSDS
  • 536709PAMAM dendrimer, ethylenediamine core, generation 5.0 solution, 5 wt. % in methanol 1 gSDS
  • 536717PAMAM dendrimer, ethylenediamine core, generation 6.0 solution, 5 wt. % in methanol 1 gSDS
  • 536725PAMAM dendrimer, ethylenediamine core, generation 7.0 solution, 5 wt. % in methanol 1 gSDS

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class

3 - Flammable liquids

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Heck reactions catalyzed by PAMAM-dendrimer encapsulated Pd (0) nanoparticles
Rahim EH, et al.
Nano Letters, 1(9), 499-501 (2001)
Esen Efeoglu et al.
The Analyst, 142(20), 3848-3856 (2017-09-13)
Although consumer exposure to nanomaterials is ever increasing, with potential increased applications in areas such as drug and/or gene delivery, contrast agents and diagnosis, the determination of the cyto- and geno-toxic effects of nanomaterials on human health and the environment
Poly (amidoamine) dendrimers as a pharmaceutical excipient. Are we there yet?
Otto DP and De Villiers MM
Journal of Pharmaceutical Sciences, 107(1), 75-83 (2018)
PAMAM dendrimer: a pH-controlled nanosponge
Maiti PK
Canadian Journal of Chemistry, 95(9), 991-998 (2017)

Artículos

Solubility Enhancement with Dendrimers

Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.

Solubility Enhancement with Dendrimers

Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.

Solubility Enhancement with Dendrimers

Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.

Solubility Enhancement with Dendrimers

Replace volatile organic solvents with water due to environmental concerns, overcoming challenges in solubility.

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