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Merck
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Key Documents

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525472

Sigma-Aldrich

D-Phenylalanine methyl ester hydrochloride

98%

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About This Item

Fórmula lineal:
C6H5CH2CH(NH2)CO2CH3 · HCL
Número de CAS:
13033-84-6
Peso molecular:
215.68
MDL number:
MFCD00066112
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24874486
NACRES:
NA.22

assay

98%

reaction suitability

reaction type: solution phase peptide synthesis

mp

159-163 °C (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

Cl[H].COC(=O)[C@H](N)Cc1ccccc1

InChI

1S/C10H13NO2.ClH/c1-13-10(12)9(11)7-8-5-3-2-4-6-8;/h2-6,9H,7,11H2,1H3;1H/t9-;/m1./s1

InChI key

SWVMLNPDTIFDDY-SBSPUUFOSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Shotaro Tsuchiyama et al.
Biotechnology progress, 23(4), 820-823 (2007-05-08)
The PST-01 protease is a metalloprotease that has zinc ion at the active center and is very stable in the presence of water-soluble organic solvents. The reaction rates and the equilibrium yields of the aspartame precursor N-carbobenzoxy-L-aspartyl-L-phenylalanine methyl ester (Cbz-Asp-Phe-OMe)
Ikuo Kira et al.
Journal of bioscience and bioengineering, 108(3), 190-193 (2009-08-12)
Screening was carried out for microorganisms able to produce N-(l-alpha-l-aspartyl)-l-phenylalanine methyl ester [APM] from l-isoasparagine and l-phenylalanine methyl ester hydrochloride. Of the 422 strains examined, 44 strains belonging to the family Enterobacteriaceae were found to produce APM. The enzyme catalyzing
J S Shin et al.
Biotechnology and bioengineering, 69(5), 577-583 (2000-07-18)
We recently demonstrated (J Am Chem Soc 121:3334-3340, 1999) that enzymatic enantioselectivity in organic solvents can be markedly enhanced by temporarily enlarging the substrate via salt formation. In the present study, this approach was expanded by finding that, in addition
C S Rosenfeld
Blood, 80(9), 2401-2405 (1992-11-01)
Phenylalanine methylester (PME), a lysosomotropic compound can be used to deplete monocytes and myeloid cells from peripheral blood and bone marrow (BM). The potential of PME for purging leukemic cells from BM was investigated using U937 and HL-60 cell lines
R D Skwierczynski et al.
Pharmaceutical research, 10(8), 1174-1180 (1993-08-01)
The kinetics of demethylation of aspartame and L-phenylalanine methyl ester were studied in aqueous solution at 25 degrees C over the pH range 0.27-11.5. The pseudo-first-order rate constant for aspartame was resolved into individual contributions from methyl ester hydrolysis and
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