444375

N-Benzoyl-(2R,3S)-3-phenylisoserine

98%

• Fórmula lineal: C₆H₅CONHCH(C₆H₅)CH(OH)CO₂H
• Número de CAS: 132201-33-3
• Peso molecular: 285.29
• MDL number: MFCD00274633
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24868119
• NACRES: NA.22

Propiedades

• assay: 98%
• optical activity: [α]20/D −40°, c = 1.0 in ethanol
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 169-172 °C (lit.)
• application(s): peptide synthesis
• SMILES string: O[C@H]([C@@H](NC(=O)c1ccccc1)c2ccccc2)C(O)=O
• InChI: 1S/C16H15NO4/c18-14(16(20)21)13(11-7-3-1-4-8-11)17-15(19)12-9-5-2-6-10-12/h1-10,13-14,18H,(H,17,19)(H,20,21)/t13-,14+/m0/s1
• InChI key: HYJVYOWKYPNSTK-UONOGXRCSA-N

Descripción

Application

The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves