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Marimastat

Name: Marimastat
Brand: SIGMA

≥98% (HPLC), solid, MMP inhibitor

Synonym(s):

BB2516, (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl] propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₂₉N₃O₅

CAS Number:

154039-60-8

Molecular Weight:

331.41

UNSPSC Code:

12352200

PubChem Substance ID:

329817950

NACRES:

NA.77

MDL number:

MFCD00866242

Assay:

≥98% (HPLC)

Form:

solid

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Properties

Product Name

Marimastat, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

solid

solubility

DMSO: ≥20 mg/mL

shipped in

wet ice

storage temp.

−20°C

SMILES string

CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C

InChI

1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1

InChI key

OCSMOTCMPXTDND-OUAUKWLOSA-N

Gene Information

—

Description

Application

Marimastat has been used as an inhibitor of:

metalloproteinase 2/9 (MMP2/9), to study its effects on exercise-mediated interleukin-6 (IL-6) release in mice
metalloproteinase, to determine protease activity in Pseudomonas aeruginosa cultures
metalloproteinase 10 (MMP10), to study its effect on monoclonal antibody H3 binding to MMP10

Biochem/physiol Actions

Marimastat is a broad spectrum matrix metalloprotease (MMP) inhibitor

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This Item	SML0041	M5942	SML0685
Sigma-Aldrich M2699 Marimastat	Sigma-Aldrich SML0041 Batimastat	Sigma-Aldrich M5942 MRS 2395	Sigma-Aldrich SML0685 Amprenavir
description ≥98% (HPLC)	description ≥98% (HPLC)	description ≥98% (HPLC), solid	description ≥98% (HPLC)
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form solid	form powder	form solid	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. −20°C	storage temp. -	storage temp. −20°C
solubility DMSO: ≥20 mg/mL	solubility DMSO: ≥15 mg/mL	solubility DMSO: >10 mg/mL, H₂O: insoluble	solubility DMSO: 20 mg/mL, clear
shipped in wet ice	shipped in wet ice	shipped in -	shipped in -

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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