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Key Documents

COO/COA

EHU090691

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human C17ORF53

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About This Item

UNSPSC Code:

41105324

NACRES:

NA.51

description

product line

MISSION^®

form

lyophilized powder

esiRNA cDNA target sequence

CAGAAGCTGTTTGCTGTGGAAGAGGAGTTTGAAGATGAGGATTTCTTGTCTGCTGTGGAGGATGCAGAGAACCGGTTTACTGGCTCACTGCCTGTGAATGCTGGGCGCCTGAGACCTGTCTCTTCTAGGCCACAGGAGACTGTGCAGGCACAGTCCTCCAGGCTGCTGCTGTTACACCCCACTGCTCCCTCAGAGGCTTTGGGCCTGCCAGACTTGGACCTCTGCCTCCCTGCCTCCAGCACGCCCAGTGCTGACAGCCGTCCATCATGCATAGGAGCAGCTCCCCTAAGGCCTGTCTCTACTTCCAGCAGCTGGATTGGCAATCAGAGAAGAGTGACAGTGACAGAAGTGCTCAGAGAGACAGCAAGACCTCAGTCCTCAGCCTTACACCCCCTACTCACCTTTGAGAGCCAACAGCAGCAAGTT

Ensembl | human accession no.

ENSG00000125319

NCBI accession no.

NM_024032

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... C17ORF53(78995) , C17orf53(78995)

Related Categories

MISSION® esiRNA

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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C17orf53 is identified as a novel gene involved in inter-strand crosslink repair.

Chao Wang et al.

DNA repair, 95, 102946-102946 (2020-08-28)

Ataxia Telangiectasia and Rad3-Related kinase (ATR) is a master regulator of genome maintenance, and participates in DNA replication and various DNA repair pathways. In a genome-wide screen for ATR-dependent fitness genes, we identified a previously uncharacterized gene, C17orf53, whose loss

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