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C4151

Sigma-Aldrich

Sodium decanoate

≥98%

Synonym(s):

Capric acid sodium salt, Decanoic acid sodium salt, Sodium caprate

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About This Item

Linear Formula:
CH3(CH2)8COONa
CAS Number:
1002-62-6
Molecular Weight:
194.25
Beilstein:
3572742
EC Number:
213-688-4
MDL number:
MFCD00066453
UNSPSC Code:
12352211
PubChem Substance ID:
24892670
NACRES:
NA.25

biological source

natural (organic)

Assay

≥98%

form

powder

functional group

ester

lipid type

saturated FAs

shipped in

ambient

storage temp.

2-8°C

SMILES string

[Na+].CCCCCCCCCC([O-])=O

InChI

1S/C10H20O2.Na/c1-2-3-4-5-6-7-8-9-10(11)12;/h2-9H2,1H3,(H,11,12);/q;+1/p-1

InChI key

FIWQZURFGYXCEO-UHFFFAOYSA-M

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Application


  • Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation.: This study elucidates how sodium decanoate affects neonatal intestinal barriers, indicating its potential for nutritional interventions to enhance mucosal immunity and gastrointestinal health (Ronholt et al., 2024).

  • Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.: Demonstrates the role of sodium decanoate in enhancing skin permeability, offering insights into its applications in transdermal drug delivery systems (Dinh et al., 2023).

  • The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil.: Highlights sodium decanoate′s impact on the intestinal absorption mechanisms, contributing to the development of more effective oral drug formulations (Dahan et al., 2022).

  • Control of Escherichia coli Serotype O157:H7 Motility and Biofilm Formation by Salicylate and Decanoate: MarA/SoxS/Rob and pchE Interactions.: Investigates how sodium decanoate influences bacterial behavior, particularly in managing pathogenicity and biofilm control, which is crucial for both clinical and environmental applications (Ream et al., 2022).

  • Sodium Decanoate Improves Intestinal Epithelial Barrier and Antioxidation via Activating G Protein-Coupled Receptor-43.: This research explores sodium decanoate′s therapeutic potential in strengthening intestinal barriers and enhancing antioxidative properties, making it a candidate for gastroenterological treatments (Ma et al., 2021).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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D Dahlgren et al.
International journal of pharmaceutics, 549(1-2), 239-248 (2018-07-29)
The small intestine mucosal barrier is physiologically regulated by the luminal conditions, where intestinal factors, such as diet and luminal tonicity, can affect mucosal permeability. The intestinal barrier may also be affected by absorption-modifying excipients (AME) in oral drug delivery
Otto Mankinen et al.
Nature communications, 11(1), 3251-3251 (2020-06-28)
The exchange of molecules between different physical or chemical environments due to diffusion or chemical transformations has a crucial role in a plethora of fundamental processes such as breathing, protein folding, chemical reactions and catalysis. Here, we introduce a method
Wei Li et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 39(5), 639-647 (2018-04-13)
Entry of locally applied drugs into the inner ear can be enhanced by chemical manipulations. Perilymph drug concentrations achieved by intratympanic applications are well below the applied concentration due to limited entry through the round window (RW) membrane and stapes.
Wei Zhou et al.
Acta pharmacologica Sinica, 33(8), 1069-1079 (2012-07-10)
To investigate the mechanisms underlying the intestinal absorption of the major bioactive component forsythoside A (FTA) extracted from Forsythiae fructus. An in vitro Caco-2 cell model and a single-pass intestinal perfusion in situ model in SD rats were used. In
Hong-Yu Xu et al.
Colloids and surfaces. B, Biointerfaces, 181, 927-934 (2019-08-07)
Berberine (BBR) is an important natural product with poor gastrointestinal behavior includes low permeability, P-glycoprotein efflux, and mass elimination in the intestine. The aim of this study was to develop a novel nanoemulsion (NE) to improve the hypoglycemic efficacy of
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