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B8263

Sigma-Aldrich

Benzphetamine hydrochloride

Synonym(s):

N-Benzyl-N,α-dimethylphenethylamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C17H21N · HCl
CAS Number:
5411-22-3
Molecular Weight:
275.82
EC Number:
226-489-2
MDL number:
MFCD00058090
UNSPSC Code:
12352116
PubChem Substance ID:
24892064
NACRES:
NA.77

form

solid

Quality Level

200

drug control

USDEA Schedule III; Home Office Schedule 3; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

SMILES string

Cl.C[C@@H](Cc1ccccc1)N(C)Cc2ccccc2

InChI

1S/C17H21N.ClH/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17;/h3-12,15H,13-14H2,1-2H3;1H/t15-;/m0./s1

InChI key

ANFSNXAXVLRZCG-RSAXXLAASA-N

Gene Information

human ... SLC18A2(6571)

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Biochem/physiol Actions

Adrenergic receptor agonist; CNS stimulant.

Certificates of Analysis (COA)

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A Fujinami et al.
Biological & pharmaceutical bulletin, 21(11), 1207-1210 (1998-12-16)
We developed a method for simultaneous analysis of benzphetamine (BZ) and its metabolites, p-hydroxy-N-benzylamphetamine (pHBA), p-hydroxybenzphetamine (pHBZ), amphetamine (AP), methamphetamine and p-hydroxymethamphetamine by micellar electrokinetic chromatography (MEKC). Urine samples from 0-15 h (3-h intervals) after oral administration of BZ (10
R de la Garza et al.
The Journal of pharmacology and experimental therapeutics, 243(3), 955-962 (1987-12-01)
Rhesus monkeys were trained to discriminate intragastrically administered d-amphetamine (AMPH) or pentobarbital (PENTO) from saline using a signaled shock-avoidance trail procedure. All monkeys maintained criterion levels (greater than 90% drug-appropriate responding) throughout the duration of the study during training sessions.

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