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Key Documents

59769

Sigma-Aldrich

Micro particles based on polystyrene

size: 500 nm

Synonym(s):

Latex beads from PS

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About This Item

MDL number:
MFCD00243243
UNSPSC Code:
12352116
NACRES:
NA.32
Pricing and availability is not currently available.

Quality Level

100

form

aqueous suspension

concentration

10% (solids)

particle size

500 nm

density

1.05 g/cm3

storage temp.

2-8°C

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General description

Micro Particles or Latex Beads, commonly known as polystyrene microparticles, are negatively charged colloidal particles. The microparticles are produced through a polymerization reaction of styrene under controlled conditions. The conducive environment of the reaction induces spontaneous coalescent bead formation. Micro Particles or Latex beads are supplied in aqueous solutions composed of polymer particles with water. Polystyrene′s refractive index at 589 nm is 1.5905 and 1.602 at 486 nm.

Application

Micro Particles or Latex Beads is used for a wide variety of applications like:

  • Electron Microscopy.
  • Cell Counter Calibration.
  • Immunodiagnostics, especially for latex agglutination tests, and
  • Phagocytosis Research.

Analysis Note

For every lot exact values of particle size and standard deviation are determined with an accuracy of 0.01 μm using a Coulter Multisizer.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM5425
BCCM1937
BCCM0796
BCCL9440
BCCL7427

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Elizabeth M Walker et al.
Journal of colloid and interface science, 363(1), 307-313 (2011-08-16)
We have studied polydimethylsiloxane (PDMS)-in-1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF(6)]) Pickering emulsions stabilized by polystyrene microparticles with different surface chemistry. Surprisingly, in contrast to the consensus originating from oil/water Pickering emulsions in which the solid particles equilibrate at the oil-water droplet interfaces and
Shunmugaperumal Tamilvanan et al.
PDA journal of pharmaceutical science and technology, 62(3), 177-190 (2008-07-30)
The objective of this study is to select a multiple-unit sustained-release formulation and to compare it with both commercial immediate and single unit sustained-release capsules and also to determine whether an in vitro-in vivo correlation exists for single- and multiple-
Sensitive Mie scattering immunoagglutination assay of porcine reproductive and respiratory syndrome virus (PRRSV) from lung tissue samples in a microfluidic chip.
Song JY, Lee CH, Choi EJ, Kim K, et al.
J. Virol. Methods, 178, 31-38 (2011)
Fiona A Sharp et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(3), 870-875 (2009-01-14)
Many currently used and candidate vaccine adjuvants are particulate in nature, but their mechanism of action is not well understood. Here, we show that particulate adjuvants, including biodegradable poly(lactide-co-glycolide) (PLG) and polystyrene microparticles, dramatically enhance secretion of interleukin-1beta (IL-1beta) by

Questions

1–3 of 3 Questions  

  1. We would like to use the PSL for an aerosol particle generator. Is there any recommended dilution?

    1 answer

    1. This solution contains 10% solids. The product is not tested for suitability in any specific application. The end user would have to determine the appropriate dilution, experimentally. A suggestion would be to initially try the solution neat followed by further serial 2 or 4 fold dilutions in an attempt to determine the optimum concentration for the application. Please see the links below to review publications which may be helpful:

      https://www.tandfonline.com/doi/full/10.1080/02786826.2013.868594

      https://www.tandfonline.com/doi/full/10.1080/02786826.2018.1505032

      Helpful?

  2. Does the material with part number 59769 contain surfactant to aid in dispersibility? Also, what is the pH of this material?

    1 answer

    1. The product polystyrene microparticles does not contain surfactants and comes in deionized water. The particles have an anionic surface charge due to sulfate groups coming from the initiator in the polymerization reaction. Additionally, the particles’ Zeta potential is in the – 50 mV region over a wide pH range from approximately 2 through 10.

      Helpful?

  3. Does this product have surfactants?

    1 answer

    1. Product 59769 - Polystyrene microparticles do not contain surfactants. The polystyrene microparticles are supplied in deionized water.

      Helpful?

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