PHR1553
N,N-Dimethylformamide
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
N,N-Dimethylformamide, DMF, NSC 5356
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About This Item
Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
Beilstein:
605365
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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product name
Dimethylformamide, Pharmaceutical Secondary Standard; Certified Reference Material
grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to USP 1601500
vapor density
2.5 (vs air)
vapor pressure
2.7 mmHg ( 20 °C)
CofA
current certificate can be downloaded
autoignition temp.
833 °F
expl. lim.
15.2 %
packaging
ampule of 3x1.2 mL each
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.430 (lit.)
bp
153 °C (lit.)
mp
−61 °C (lit.)
density
0.944 g/mL (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
[H]C(=O)N(C)C
InChI
1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
InChI key
ZMXDDKWLCZADIW-UHFFFAOYSA-N
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dimethylformamide is a polar solvent commonly used in organic synthesis, isolation of chlorophyll from plant tissues, etc. It also acts as a multipurpose precursor for formylation, amination, amino carbonylation, amidation and cyanation reactions.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Solvent for many hydrophobic organic compounds.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC2887 in the slot below. This is an example certificate only and may not be the lot that you receive.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
135.5 °F - closed cup
Flash Point(C)
57.5 °C - closed cup
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