M1511
Sodium 2-mercaptoethanesulfonate
analytical standard, ≥98.0% (titration)
Synonym(s):
2-Mercaptoethanesulfonic acid sodium salt, Coenzyme M sodium salt, HS-CoM Na, MESNA
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
HSCH2CH2SO3Na
CAS Number:
Molecular Weight:
164.18
Beilstein:
3657828
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
Assay
≥98.0% (titration)
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
SMILES string
[Na+].[O-]S(=O)(=O)CCS
InChI
1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1
InChI key
XOGTZOOQQBDUSI-UHFFFAOYSA-M
Looking for similar products? Visit Product Comparison Guide
General description
Sodium 2-mercaptoethanesulfonate is a thiol compound commonly used as an auxiliary drug, to reduce the side effects of anti-cancer drugs, such as oxazaphosphorine, cyclophosphamide, and ifosfamide. It acts by forming a non-toxic compound upon reacting with the toxic metabolites of the drugs like acrolein.
Application
The analytical standard can also be used as follows:
- Quantification of sodium 2-mercaptoethanesulfonate (MESNA) from human samples by micellar electrokinetic chromatography (MEKC) coupled with UV detection and in-capillary derivatization of MESNA
- Development of a fluorescence-enhanced histidine stabilized gold nanoclusters (His-Au NCs) based probe for the detection of sodium 2-mercaptoethanesulfonate in uromitexan samples
- High-performance liquid chromatography-tandem mass spectrometric based bioanalysis of sodium 2-mercaptoethanesulfonate in rat plasma samples
- To quantify sodium 2-mercaptoethanesulfonate in two of its pharmaceutical preparations (injections) by surface-enhanced Raman scattering (SERS) using gold colloid as a probe
Other Notes
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Jun-ichi Nishigaki et al.
Inorganic chemistry, 51(6), 3690-3697 (2012-03-10)
Divalent and trivalent nickel complexes of 1,4,8,11-tetraazacyclotetradecane, denoted as cyclam hereafter, coordinated by methyl coenzyme M (MeSCoM(-)) and coenzyme M (HSCoM(-)) have been synthesized in the course our model studies of methyl coenzyme M reductase (MCR). The divalent nickel complexes
Muhammad Faizan Nazar et al.
Journal of colloid and interface science, 363(2), 490-496 (2011-08-27)
A viable cost-effective approach employing mixtures of non-ionic surfactants Triton X-114/Triton X-100 (TX-114/TX-100), and subsequent cloud point extraction (CPE), has been utilized to concentrate and recycle inorganic nanoparticles (NPs) in aqueous media. Gold Au- and palladium Pd-NPs have been pre-synthesized
Twalib Ngoma et al.
British journal of haematology, 158(6), 749-762 (2012-08-01)
Prior to the introduction of the International Network for Cancer Treatment and Research (INCTR) protocol INCTR 03-06, survival of patients with Burkitt lymphoma at four tertiary care centres in equatorial Africa was probably no more than 10-20%. The results reported
Frank Thomas et al.
Applied and environmental microbiology, 77(24), 8669-8675 (2011-10-18)
In spite of the significant impact of biomethylation on the mobility and toxicity of metals and metalloids in the environment, little is known about the biological formation of these methylated metal(loid) compounds. While element-specific methyltransferases have been isolated for arsenic
Erdal Resit Yilmaz et al.
Acta neurochirurgica, 155(1), 141-149 (2012-10-12)
The agent, 2-mercaptoethane sulfonate (MESNA), is a synthetic small molecule, widely used as a systemic protective agent against chemotherapy toxicity, but is primarily used to reduce hemorrhagic cystitis induced by cyclophosphamide. Because MESNA has potential antioxidant and cytoprotective effects, so
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service