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84230

Sigma-Aldrich

Salicylamide

puriss., ≥99.0% (T)

Synonym(s):

2-Hydroxybenzamide

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About This Item

Linear Formula:
2-(HO)C6H4CONH2
CAS Number:
Molecular Weight:
137.14
Beilstein:
742439
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

puriss.

Quality Level

Assay

≥99.0% (T)

form

solid

mp

139-141 °C
140-144 °C (lit.)

solubility

methanol: 0.1 g/mL, clear

SMILES string

NC(=O)c1ccccc1O

InChI

1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)

InChI key

SKZKKFZAGNVIMN-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J A Murillo Pulgarín et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 909-914 (2011-05-13)
A new methodology for the simultaneous determination of salicylic acid and salicylamide in biological fluids is proposed. The strong overlapping of the fluorescence spectra of both analytes makes impossible the conventional fluorimetric determination. For that reason, the use of fluorescence
R Dolezal et al.
European journal of medicinal chemistry, 44(2), 869-876 (2008-06-13)
Quantitative relationships between the molecular structure and the biological activity of 49 isosteric salicylamide derivatives as potential antituberculotics with a new mechanism of action against three Mycobacterial strains were investigated. The molecular structures were represented by quantum chemical B3LYP/6-31G( *)
Stephanie S Barnes et al.
Dalton transactions (Cambridge, England : 2003), 40(17), 4707-4714 (2011-03-25)
Addition of boranes to N-aryl-salicylaldimines takes place initially at the reactive phenolic O-H bond to give an activated boron-containing imine and dihydrogen. In some cases a subsequent intramolecular hydrogenation step is observed and the C=N imine bond is reduced to
S Zhang et al.
Transplantation proceedings, 38(5), 1247-1252 (2006-06-27)
Cardiac ischemia/reperfusion (I/R) injury, a necessary consequence of transplantation, is probably related to the formation of reactive oxygen species (ROS). The ROS burst within the first moments of reperfusion is associated with injury, continuously generate O2- at about 3% to
Silvia Wein et al.
Xenobiotica; the fate of foreign compounds in biological systems, 42(5), 477-482 (2011-12-23)
We investigated acute effects and effects after chronic intake of the orally administered flavonol quercetin on pharmacokinetics of salicylamide metabolites (SAM) after oral administration of salicylamide in pigs. Salicylamide (8 mg/kg body weight) was orally administered to seven pigs either

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