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GF300

Sigma-Aldrich

Activin A Protein, Human Recombinant Animal Free

Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release.

Synonym(s):

Inhibin, Activin-A, Erythroid differentiation protein

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.77

Quality Level

Assay

>97% (SDS-PAGE and HPLC)

manufacturer/tradename

Chemicon®

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

UniProt accession no.

shipped in

dry ice

General description

Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Activin proteins have a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and roles in reproductive physiology. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
Product Source: E. coli

Specificity

Cross Reactivty
Chicken, Dog, Frog, Mouse, Human and Mouse

Application

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

Quality

Bioactivity assay: determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

Physical form

Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human Activin A is manufactured using all non-animal reagents

Storage and Stability

Store at -20°C for up to 6 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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