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About This Item
Linear Formula:
HOC6H3(NO2)CH2CO2H
CAS Number:
Molecular Weight:
197.14
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
99%
mp
146-148 °C (lit.)
solubility
ethanol: soluble 5%, clear, yellow to orange
functional group
carboxylic acid
nitro
SMILES string
OC(=O)Cc1ccc(O)c(c1)[N+]([O-])=O
InChI
1S/C8H7NO5/c10-7-2-1-5(4-8(11)12)3-6(7)9(13)14/h1-3,10H,4H2,(H,11,12)
InChI key
QBHBHOSRLDPIHG-UHFFFAOYSA-N
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General description
4-Hydroxy-3-nitrophenylacetic acid enhances the ice-nucleation activity of Xanthomonas campestris.
Application
4-Hydroxy-3-nitrophenylacetic acid was used in the synthesis of 4-hydroxy-3-nitrophenylacetyl caproic acid.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Tarique Khan et al.
Journal of immunology (Baltimore, Md. : 1950), 188(4), 1819-1827 (2012-01-24)
The mechanistic basis for efficient combating of the infinite range of foreign Ags by the limited repertoire of naive Abs expressed on primary B cell surfaces during their first encounter was addressed through elegantly designed crystallographic analyses. Resolution of the
Jennifer L Marshall et al.
European journal of immunology, 41(12), 3506-3512 (2011-09-21)
Rapid production of neutralizing antibody can be critical for limiting the spread of infection. Such early antibody results when B-cell blasts mature directly to plasmablasts without forming germinal centers. These extrafollicular responses can involve Ig class switch recombination (CSR), producing
Sanjiv A Luther et al.
European journal of immunology, 37(6), 1476-1484 (2007-05-17)
For weeks after primary immunization with thymus-dependent antigens the responding lymph nodes contain effector CD4 T cells in T zones and germinal centers as well as recirculating memory T cells. Conversely, remote nodes, not exposed to antigen, only receive recirculating
Masayuki Oda et al.
Molecular immunology, 47(2-3), 357-364 (2009-10-06)
The effect of antibody affinity on molecular forms of immune complexes was investigated by measuring antigen-antibody interactions using surface plasmon resonance (SPR), electrospray ionization time-of-flight mass spectrometry under non-denaturing conditions (MS), analytical ultracentrifugation (AUC), and transmission electron microscopy (TEM). (4-Hydroxy-3-nitrophenyl)acetic
Matthew D Taylor et al.
Frontiers in immunology, 11, 1946-1946 (2020-09-10)
Recent studies have demonstrated that induction of a diverse repertoire of memory T cells ("immune education") affects responses to murine cecal ligation and puncture (CLP), the most widely - used animal model of sepsis. Among the documented effects of immune
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