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200077

Sigma-Aldrich

Arsenic(III) chloride

99.99% trace metals basis

Synonym(s):

Arsenic trichloride

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About This Item

Linear Formula:
AsCl3
CAS Number:
7784-34-1
Molecular Weight:
181.28
EC Number:
232-059-5
MDL number:
MFCD00014165
UNSPSC Code:
12352302
PubChem Substance ID:
24851956

Quality Level

100

Assay

99.99% trace metals basis

form

liquid

impurities

≤150.0 ppm Trace Metal Analysis

bp

130.2 °C (lit.)

mp

−16 °C (lit.)

density

2.15 g/mL at 25 °C (lit.)

SMILES string

Cl[As](Cl)Cl

InChI

1S/AsCl3/c2-1(3)4

InChI key

OEYOHULQRFXULB-UHFFFAOYSA-N

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General description

Arsenic(III) chloride can be used as a precursor to synthesize As-based nanocrystal alloys for thermoelectric materials and biarsenical ligands protein labeling.

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Statements

H300 + H310,H331,H410

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Young-Hee Kang et al.
Cancer research, 64(24), 8960-8967 (2004-12-18)
Although mechanisms of arsenic trioxide (As(2)O(3))-induced cell death have been studied extensively in hematologic cancers, those in solid cancers have yet to be clearly defined. In this study, we showed that the translocation of apoptosis-inducing factor (AIF) from mitochondria to
Xiaoqing He et al.
The Journal of pharmacology and experimental therapeutics, 332(1), 66-75 (2009-10-08)
Arsenic activates nuclear factor erythroid 2-related factor 2 (Nrf2) to induce phase II and antioxidative genes. Here we analyzed arsenic-Kelch-like ECH-associated protein 1 (Keap1) cysteine thiol interaction in Nrf2 activation. Arsenic-based Nrf2 activators, fluorescent biarsenical labeling reagent (FlAsH) and phenylarsine
Yue-Yong Zhu et al.
Zhongguo shi yan xue ye xue za zhi, 13(5), 778-782 (2005-11-10)
To explore the effects of vascular endothelial growth factor (VEGF) on the mechanisms of CML pathogenesis, the effect of VEGF on K562 cell apoptosis induced by As(2)O(3) was analyzed through morphologic observation, DNA fragmentation agarose gel electrophoresis and DNA ploidy
Z Y Wang
Cancer chemotherapy and pharmacology, 48 Suppl 1, S72-S76 (2001-10-06)
In this paper the use of arsenic compounds as anticancer agents in clinical trials and in in vitro investigations is reviewed, including the experience at our institute. Treatment of newly diagnosed and relapsed patients with acute promyelocytic leukemia (APL) with
Ömer Kaan Koç et al.
Mikrochimica acta, 187(10), 586-586 (2020-10-01)
As a first of its kind, we developed a highly sensitive colorimetric nanoprobe for phytic acid (PA) and Fe(III) ion detection based on 4-mercaptophenol (4MP) and thioglycolic acid (TGA)-functionalized gold nanoparticles {AuNPs@(4MP-TGA)}. AuNPs were easily derivatized by 4MP and TGA
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