All Photos(1)
About This Item
Linear Formula:
CH3(CH2)21OH
CAS Number:
Molecular Weight:
326.60
Beilstein:
1770470
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
98%
bp
180 °C/0.22 mmHg (lit.)
mp
65-72 °C (lit.)
SMILES string
CCCCCCCCCCCCCCCCCCCCCCO
InChI
1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3
InChI key
NOPFSRXAKWQILS-UHFFFAOYSA-N
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General description
1-Docosanol inhibits replication of certain viruses (herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. It has been isolated from Clematis brevicaudata.
Application
1-Docosanol was used in the synthesis of series of amphiphilic dendrimers with hydrophilic aliphatic polyether-type dendritic core and hydrophobic docosyl peripheries.
Storage Class Code
11 - Combustible Solids
WGK
nwg
Flash Point(F)
410.0 °F
Flash Point(C)
210 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Ai-Mei Yang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(10), 1534-1537 (2010-02-02)
To study the chemical constituents from Clematis brevicaudata. The compounds were isolated by column chromatography and their structures were elucidated through spectroscopic analysis (NMR). Eight compounds were isolated and identified as: palmitic acid (1), 1-docosanol (2), pentacosanoic acid-2', 3'-dihydroxypropyl ester
Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex.
D H Katz et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(23), 10825-10829 (1991-12-01)
This article reports that 1-docosanol, a 22-carbon-long saturated alcohol, exerts a substantial inhibitory effect on replication of certain viruses (e.g., herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. To study the basis for its viral
Synthesis and self-assembly of amphiphilic dendrimers based on aliphatic polyether-type dendritic cores.
Cho B-K, et al.
Macromolecules, 37(11), 4227-4234 (2004)
Guadalupe Iglesias et al.
Regulatory toxicology and pharmacology : RTP, 36(1), 80-85 (2002-10-18)
Behenyl alcohol is a saturated 22-carbon, long-chain aliphatic alcohol, which has potential for use in foods as an oil-structuring and -solidifying agent in fats. Previously completed studies with behenyl alcohol indicated an absence of mutagenic or genotoxic potential. In addition
Clara L Shaw et al.
Journal of chemical ecology, 37(4), 329-339 (2011-03-23)
The uropygial secretions of some bird species contain volatile and semivolatile compounds that are hypothesized to serve as chemical signals. The abundance of secretion components varies with age and season, although these effects have not been investigated in many species.
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