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130532

Sigma-Aldrich

5,7-Dichloro-8-hydroxy-2-methylquinoline

98%

Synonym(s):

5,7-Dichloro-2-methyl-8-quinolinol, 5,7-Dichloro-8-hydroxyquinaldine, 5,7-Dichloro-8-quinaldinol, BCM

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About This Item

Empirical Formula (Hill Notation):
C10H7Cl2NO
CAS Number:
Molecular Weight:
228.07
Beilstein:
156683
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

mp

108-112 °C (dec.) (lit.)

SMILES string

Cc1ccc2c(Cl)cc(Cl)c(O)c2n1

InChI

1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3

InChI key

GPTXWRGISTZRIO-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A double-blind comparative study to compare the efficacy of Locoid C with Tri-Adcortyl in children with infected eczema.
F O Meenan
The British journal of clinical practice, 42(5), 200-202 (1988-05-01)
I Corrihons et al.
Pathologie-biologie, 39(2), 136-139 (1991-02-01)
The activity of chlorquinaldol, a derivative of hydroxy-8-quinolein used for local antisepsy, was studied against Neisseria gonorrhoeae and Chlamydia trachomatis. The weak solubility of the product and the special growth conditions of the organisms made an adaptation of the AFNOR
M Miścicka et al.
Acta poloniae pharmaceutica, 47(3-4), 25-28 (1990-01-01)
Chromatographic conditions for the separation of five pairs of active compounds occuring in four ointment preparations and an aerosol one were elaborated. The ways of extraction of hydrocortisone esters (acetate and butyrate), chlorquinaldol, oxytetracycline base and oxytetracycline hydrochloride from the
Contact cross-sensitization among quinolines.
A Rodríguez et al.
Allergy, 56(8), 795-795 (2001-08-08)
Tzu-Shean Feng et al.
Biochemical pharmacology, 82(3), 236-247 (2011-05-21)
4-Aminoquinolines were hybridized with artemisinin and 1,4-naphthoquinone derivatives via the Ugi-four-component condensation reaction, and their biological activities investigated. The artemisinin-containing compounds 6a-c and its salt 6c-citrate were the most active target compounds in the antiplasmodial assays. However, despite the potent

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