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Key Documents

G9005

Sigma-Aldrich

D-Gluconic acid sodium salt

≥99% (HPLC)

Synonym(s):

2,3,4,5,6-Pentahydroxycaproic acid sodium salt, D-Gluconate sodium salt, Sodium D-gluconate

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About This Item

Empirical Formula (Hill Notation):
C6H11NaO7
CAS Number:
Molecular Weight:
218.14
Beilstein:
3919651
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

microbial

Quality Level

Assay

≥99% (HPLC)

form

powder or crystals

technique(s)

HPLC: suitable

color

white to off-white

useful pH range

6.5-7.5

mp

170-175  °C

solubility

590 g/L at 25 °C

application(s)

agriculture

storage temp.

room temp

SMILES string

[Na+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H12O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1

InChI key

UPMFZISCCZSDND-JJKGCWMISA-M

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Application

D-Gluconic acid sodium salt has been used:
  • as a component to make synthetic interstitial fluid.
  • used as a carbohydrate.
  • used as a substitute for sodium chloride to make chlorine (Cl-) free media.

Biochem/physiol Actions

D-Gluconic acid is a mild organic acid with non-corrosive, non-odorous, non-volatile and biodegradable property. Enzymatic conversion of D-Glucose results in the final product D-Gluconic acid. Gluconic acid occurs from the oxidation of glucose and is naturally in fruit, honey and wine. When used as a food additive it helps regulate acidity. Sodium salt of D-gluconic acid is a strong chelating agent, chelating the anions of calcium, iron, aluminium, copper, and other heavy metals. It finds wide application in detergent industry for bottle washing, descaling of salt deposits and alkaline derusting. D-Gluconic acid usage as an additive in cement, gives strength and water resistance.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Serratia marcescens quinoprotein glucose dehydrogenase activity mediates medium acidification and inhibition of prodigiosin production by glucose.
Fender JE, et al.
Applied and Environmental Microbiology, AEM-01778 (2012)
Phenotyping sensory nerve endings in vitro in the mouse
Zimmermann K, et al.
Nature Protocols, 4(2), 174-196 (2009)
Gluconic acid: Properties, applications and microbial production.
Ramachandran S, et al.
Food Technology and Biotechnology, 44(2), 185-195 (2006)
Evaluation of intracellular pH regulation and alkalosis defense mechanisms in preimplantation embryos
Dagilgan S, et al.
Theriogenology, 83(6), 1075-1084 (2015)
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Communications biology, 3(1), 328-328 (2020-06-27)
Magnetic resonance (MR) spectroscopy has potential to non-invasively detect metabolites of diagnostic significance for precision oncology. Yet, many metabolites have similar chemical shifts, yielding highly convoluted 1H spectra of intact biological material and limiting diagnostic utility. Here, we show that

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