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Y0000833

Clopamide

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Chloro-N-(2,6-dimethylpiperidinyl)-3-sulfamoylbenzamide

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About This Item

Empirical Formula (Hill Notation):
C14H20ClN3O3S
CAS Number:
Molecular Weight:
345.84
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

clopamide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]1CCC[C@H](C)N1NC(=O)c2ccc(Cl)c(c2)S(N)(=O)=O

InChI

1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+

InChI key

LBXHRAWDUMTPSE-AOOOYVTPSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clopamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Validated liquid chromatography?tandem mass spectrometry method for simultaneous determination of clopamide, reserpine and dihydroergotoxine: Application to pharmacokinetics in human plasma.
El-Din M M S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 125, 236-244 (2016)
High-performance liquid chromatographic determination of xipamide and clopamide in pharmaceuticals.
Sane R T, et al.
Journal of Chromatography A, 356, 468-472 (1986)
The Medical journal of Australia, 150(11), 646-646 (1989-06-05)
In an open study that was conducted in general practice, 22 patients with previously-untreated mild hypertension received an average daily dose of 11.7 mg of pindolol over a 50-week study period. The total cholesterol, high-density lipoprotein fraction and plasma triglyceride
Lucie Nováková et al.
Analytica chimica acta, 853, 637-646 (2014-12-04)
The conditions for the analysis of selected doping substances by UHPSFC-MS/MS were optimized to ensure suitable peak shapes and maximized MS responses. A representative mixture of 31 acidic and basic doping agents was analyzed, in both ESI+ and ESI- modes.
Lucie Nováková et al.
Analytica chimica acta, 853, 647-659 (2014-12-04)
The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical properties was analyzed using two separation techniques, namely UHPLC-MS/MS and

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