81942

Propionic anhydride

purum, ≥96.0% (NT)

• Synonym(s): Propanoic anhydride
• Linear Formula: (CH₃CH₂CO)₂O
• CAS Number: 123-62-6
• Molecular Weight: 130.14
• Beilstein: 507066
• EC Number: 204-638-2
• MDL number: MFCD00009303
• UNSPSC Code: 12352100
• PubChem Substance ID: 329769224
• NACRES: NA.22

Properties

• vapor density: 4.5 (vs air)
• Quality Level: 200
• vapor pressure: 10 mmHg ( 57.7 °C)
• grade: purum
• Assay: ≥96.0% (NT)
• form: liquid
• autoignition temp.: 545 °F
• expl. lim.: 11.9 %
• refractive index: n20/D 1.404 (lit.); n20/D 1.404
• bp: 167 °C (lit.)
• mp: −43 °C (lit.)
• solubility: H₂O: decomposes (when in contact with water)
• density: 1.010 g/mL at 20 °C; 1.015 g/mL at 25 °C (lit.)
• SMILES string: CCC(=O)OC(=O)CC
• InChI: 1S/C6H10O3/c1-3-5(7)9-6(8)4-2/h3-4H2,1-2H3
• InChI key: WYVAMUWZEOHJOQ-UHFFFAOYSA-N

Description

Application

Propionic anhydride can be used:

• As an esterifying reagent in the modification of cassava starch by acylation reaction.
• As a reactant along with anisole in the synthesis of 4-methoxypropiophenone using various solid acid catalysts via Friedel−Crafts acylation reaction.
• As a reagent in the synthesis of cyanohydrin esters by treating KCN with aldehyde in presence of bimetallic titanium(salen) complex catalyst.

Other Notes

Sales restrictions may apply

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): 165.2 °F - closed cup
• Flash Point(C): 74 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves