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Arachidonyl-L-carnitine

analytical standard

Synonym(s):

C20:4(n-6) carnitine, (2R)-3-Carboxy-N,N,N-trimethyl-2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]oxy]-1-propanaminium inner salt, Arachidonoylcarnitine

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About This Item

Empirical Formula (Hill Notation):
C27H45NO4
CAS Number:
Molecular Weight:
447.65
UNSPSC Code:
41116107
NACRES:
NB.21

grade

analytical standard

Quality Level

Assay

≥95.0% (LC/MS)

optical activity

[α]/D -13±3°, c = 0.1 in methanol

shelf life

limited shelf life, expiry date on the label

application(s)

clinical testing

format

neat

storage temp.

−20°C

SMILES string

[O-]C(C([H])([H])[C@](OC(C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])/C([H])=C([H])\C([H])([H])/C([H])=C([H])\C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)([H])C([H])([H])[N+](C([H])([H])[H])(C([H]

General description

Arachidonyl-L-carnitine belongs to the class of long-chain acylcarnitines, a wide range of metabolites, derived from their cognate acyl-CoAs. They serve as good biomarkers for perturbations of a multitude of distinct metabolic pathways.

Application

Arachidonyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in cultured cells using hydrophilic interaction liquid chromatography (HILIC) and liquid chromatography–electrospray ionization tandem mass spectrometry (LC–ESI-MS/MS).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol
Weng L, et al.
Metabolomics, 12(10), 160-160 (2010)
A new LC?ESI-MS/MS method to measure long-chain acylcarnitine levels in cultured cells
Jauregui O, et al.
Analytica Chimica Acta, 599(1), 1-6 (2007)

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