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447706

Sigma-Aldrich

5-Chlorosalicylaldehyde

98%

Synonym(s):

2-Hydroxy-5-chlorobenzaldehyde, 3-Chloro-6-hydroxybenzaldehyde, 4-Chloro-2-formylphenol, 5-Chloro-2-hydroxybenzaldehyde, 5-Chloro-o-salicylaldehyde, 5-Chlorosalicyaldehyde

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About This Item

Linear Formula:
ClC6H3(OH)CHO
CAS Number:
635-93-8
Molecular Weight:
156.57
EC Number:
211-244-4
MDL number:
MFCD00003331
UNSPSC Code:
12352100
PubChem Substance ID:
24868354
NACRES:
NA.22

Assay

98%

form

solid

mp

100-102 °C (lit.)

SMILES string

Oc1ccc(Cl)cc1C=O

InChI

1S/C7H5ClO2/c8-6-1-2-7(10)5(3-6)4-9/h1-4,10H

InChI key

FUGKCSRLAQKUHG-UHFFFAOYSA-N

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Related Categories

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H315,H319,H335,H400

Hazard Classifications

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Yan Peng et al.
Chemical & pharmaceutical bulletin, 62(3), 221-228 (2014-03-04)
A new platinum(II) complex of salphen derivative, namely Schiff base ligand that derived from o-phenylenediamine and 5-chlorosalicylaldehyde was synthesized. The complex possessed a planar mononuclear structure. The in vitro cytotoxicities of the complex were evaluated by microculture tetrozolium (MTT) assay
Kanalli V Ajeya et al.
Journal of hazardous materials, 399, 123047-123047 (2020-09-18)
To recover the spent vanadium compound, Rhodamine-B-based Schiff's base ligand (L1) was synthesized via ultrasonication process and was evaluated with vanadyl sulfate (VOSO4), which has shown considerable selectivity towards V(IV). The change of the solution color from colorless to pink
Verónica Ferraresi-Curotto et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 137, 692-700 (2014-09-26)
Five Schiff bases obtained from condensation of 4-methoxybenzohydrazide with related aldehydes, namely o-vanillin, vanillin, 5-bromovanillin, 5-chlorosalicylaldehyde and 5-bromosalicylaldehyde were prepared. A detailed structural and spectroscopic study is reported. The crystal structures of four members of the family were determined and
Xiaotong Chen et al.
Analytica chimica acta, 625(1), 41-46 (2008-08-30)
A facile fluorescent method for the determination of hydrazine in aqueous solution with excellent sensitivity was developed. 5-chlorosalicylaldehyde (CS), a readily commercially available compound, was applied as the derivatization reagent in this work. Under the addition of CS to hydrazine
Khalid Mahmood et al.
Journal of biomolecular structure & dynamics, 38(6), 1670-1682 (2019-05-11)
In search of achieving less toxic and more potent chemotherapeutics, three novel heterocyclic benzimidazole derivatives: 2-(1H-benzo[d]imidazol-2-yl)-4-chlorophenol (BM1), 4-chloro-2-(6-methyl-1H-benzo[d]imidazol-2-yl)phenol (BM2) and 4-chloro-2-(6-nitro-1H-benzo[d]imidazol-2-yl)phenol (BM3) with DNA-targeting properties, were synthesized and fully characterized by important physicochemical techniques. The DNA binding properties of the
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