58970-U

SUPELCOSIL^™ LC-18-T (3 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

• Synonym(s): LC-18-T HPLC Column
• UNSPSC Code: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Properties

• product name: SUPELCOSIL^™ LC-18-T HPLC Column, 3 μm particle size, L × I.D. 15 cm × 4.6 mm
• material: stainless steel column
• Quality Level: 100
• Agency: suitable for USP L1
• product line: SUPELCOSIL^™
• feature: endcapped
• manufacturer/tradename: SUPELCOSIL^™
• packaging: 1 ea of
• extent of labeling: 12.3% carbon loading
• parameter: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• technique(s): HPLC: suitable
• L × I.D.: 15 cm × 4.6 mm
• surface area: 170 m²/g
• surface coverage: surface coverage 3.1 μmol/m²
• matrix: silica gel, spherical particle platform; fully porous particle
• matrix active group: C18 (octadecyl) phase
• particle size: 3 μm
• pore size: 120 Å
• operating pH: 2-7.5
• application(s): food and beverages
• separation technique: reversed phase

Description

General description

SUPELCOSIL LC-18-T columns feature an octadecylsilane bonded phase and a special surface treatment for efficient separations of nucleotides. Each batch of packing material is tested to ensure good peak shape for a representative nucleotide, adenosine diphosphate (ADP). Chromatography of other compounds that exhibit metal chelating properties also can be improved by using this phase.

Application

• A new validated HPLC method for the determination of quercetin: Application to study pharmacokinetics in rats.: This study utilizes the SUPELCOSIL LC-18-T HPLC Column to develop a new HPLC method for the determination of quercetin, significantly enhancing the ability to study its pharmacokinetics in biological samples. The research not only improves our understanding of quercetin′s therapeutic effects but also aids in optimizing its dosage for better clinical outcomes. The robust method ensures accurate and reproducible results, critical for advancing pharmacological research and supporting health sciences (Abdelkawy et al., 2017).

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Legal Information

SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves