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T9753

Sigma-Aldrich

D-Tryptophan

≥98.0% (HPLC)

Synonym(s):

(R)-2-Amino-3-(3-indolyl)propionic acid, D-α-Amino-3-indolepropionic acid

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About This Item

Empirical Formula (Hill Notation):
C11H12N2O2
CAS Number:
Molecular Weight:
204.23
Beilstein:
86198
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.32

product name

D-Tryptophan, ≥98.0% (HPLC)

biological source

synthetic (organic)

Assay

≥98.0% (HPLC)

form

powder

technique(s)

cell culture | embryo: suitable
cell culture | mammalian: suitable

color

white to off-white

mp

282-285 °C (dec.) (lit.)

SMILES string

N[C@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1

InChI key

QIVBCDIJIAJPQS-SECBINFHSA-N

Gene Information

human ... GRINA(2907)
mouse ... GRINA(66168)
rat ... GRINA(266668)

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General description

Tryptophan is one of the essential and standard amino acids present in the body. It is used by the cells to produce proteins.

Application

D-Tryptophan has been used to study its efficacy on dispersing biofilm in dental unit waterlines (DUWLs) in vitro.
D-Tryptophan can be used for Human embryonic kidney cell (HEK-293, ATCC: CRL-1573) culture.The product is a sweetener used to study the release of incretins from enteroendocrine cells triggered by sugar but not by sweeteners.

Biochem/physiol Actions

Low level of D-tryptophan is capable of preventing the growth of an L-tryptophan-requiring mutant of the E. coli.

Other Notes

Unnatural isomer of tryptophan.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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C F Morris et al.
Plant physiology, 88(2), 435-440 (1988-10-01)
An endogenous germination inhibitor(s) in wheat (Triticum aestivum L.) grain has been implicated in seed dormancy and germination, but its identity and mode of action have not been elucidated. We isolated and identified an endogenous germination inhibitor in white wheat
Application of D-Amino Acids as Biofilm Dispersing Agent in Dental Unit Waterlines
Ampornaramveth RS, et al.
International journal of dentistry, 2018(4954) (2018)
William Bacchus et al.
Metabolic engineering, 15, 144-150 (2012-11-28)
Prokaryotic transcriptional regulatory elements are widely utilized building blocks for constructing regulatory genetic circuits adapted for mammalian cells and have found their way into a broad range of biotechnological applications. Prokaryotic transcriptional repressors, fused to eukaryotic transactivation or repression domains
Substances Involved in Neurotransmission
Nutritional and Herbal Therapies for Children and Adolescents, 71-99 (2010)
Action of D-Tryptophan on E. coli
Hatanaka M
Nature, 204(4954), 202-203 (1964)

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