144657
Trifluoroacetamide
97%
Synonym(s):
2,2,2-Trifluoroacetamide
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About This Item
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Assay
97%
form
solid
bp
162.5 °C (lit.)
mp
65-70 °C (lit.)
functional group
amide
SMILES string
NC(=O)C(F)(F)F
InChI
1S/C2H2F3NO/c3-2(4,5)1(6)7/h(H2,6,7)
InChI key
NRKYWOKHZRQRJR-UHFFFAOYSA-N
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General description
Trifluoroacetamide is a good quencher of tryptophan fluorescence.
Application
Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Trifluoroacetamide was found to be a good quencher of tryptophan fluorescence, and the quenching was shown to proceed via both a dynamic and a static process. The respective quenching constants were determined by the measurement of the decrease of the
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