Skip to Content
Merck
All Photos(1)

Documents

130648

Sigma-Aldrich

4-Nitroacetanilide

98%

Synonym(s):

4′-Nitroacetanilide, Acetic acid 4-nitroanilide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CONHC6H4NO2
CAS Number:
104-04-1
Molecular Weight:
180.16
Beilstein:
2211962
EC Number:
203-169-0
MDL number:
MFCD00007303
UNSPSC Code:
12352100
PubChem Substance ID:
24847974
NACRES:
NA.22

Quality Level

100

Assay

98%

mp

213-215 °C (lit.)

SMILES string

CC(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C8H8N2O3/c1-6(11)9-7-2-4-8(5-3-7)10(12)13/h2-5H,1H3,(H,9,11)

InChI key

NQRLPDFELNCFHW-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

4-Nitroacetanilide was used as a test substrate and its hydrolysis was determined by UV spectroscopic measurements. It was also used to prepare 4-aminoacetanilide.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

María F Montenegro et al.
Biological chemistry, 389(4), 425-432 (2008-01-23)
Apart from its esterase activity, butyrylcholinesterase (BuChE) displays aryl acylamidase (AAA) activity able to hydrolyze o-nitroacetanilide (ONA) and its trifluoro-derivative (F-ONA). We report here that, despite amidase and esterase sites residing in the same protein, in human samples depleted of
Short-column liquid chromatographic assay for caffeine and chloramphenicol in serum.
R S Markin et al.
Journal of chromatography, 525(2), 464-470 (1990-02-23)
Hydrolysis of aromatic amides as assay for carboxylesterases-amidases.
E Heymann et al.
Methods in enzymology, 77, 405-409 (1981-01-01)
Ross L Stein
Biochemistry, 41(3), 991-1000 (2002-01-16)
Aryl acylamidase (EC 3.1.5.13; AAA) catalyzes the hydrolysis of p-nitroacetanilide (PNAA) via the standard three-step mechanism of serine hydrolases: binding of substrate (K(s)), acylation of active-site serine (k(acyl)), and hydrolytic deacylation (k(deacyl)). Key mechanistic findings that emerged from this study
Somnath M Kashid et al.
The journal of physical chemistry. B, 123(40), 8419-8424 (2019-09-19)
Ion-specific effects on peptides and proteins are key to biomolecular structure and stability. The subtle roles of the cations are far less understood, compared to the pronounced effects of the anions on proteins. Most importantly, divalent cations such as Ca2+
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service