S4449
Seppro® Neutralization Buffer
Synonym(s):
Tris (hydroxymethyl) aminomethane buffer
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About This Item
UNSPSC Code:
41106500
NACRES:
NA.32
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General description
Seppro® Neutralization buffer [Tris (hydroxymethyl) aminomethane] is a reagent qualified for use in Seppro® protein preparation and separation systems.
Application
Seppro® neutralization buffer has been used to neutralize the column for immunoglobulin Y (IgY) immunodepletion of top abundant plasma proteins. It has also been used for IgY14 and SuperMix depletion of human plasma.
Legal Information
Seppro is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Simon Sheng et al.
Methods in molecular biology (Clifton, N.J.), 728, 29-46 (2011-04-07)
Serum- and plasma-based biomarker discovery requires technologies with specific capabilities: sufficient proteome coverage and depth, technical reproducibly, and the scalability to enable analysis on a large number of samples at reasonable cost. We have shown that plasma samples processed using
Hasmik Keshishian et al.
Nature protocols, 12(8), 1683-1701 (2017-07-28)
Proteomic characterization of blood plasma is of central importance to clinical proteomics and particularly to biomarker discovery studies. The vast dynamic range and high complexity of the plasma proteome have, however, proven to be serious challenges and have often led
Majlinda Kullolli et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 939, 10-16 (2013-10-05)
Human plasma is a commonly used diagnostic fluid in clinical chemistry. In-depth plasma proteomic analysis is performed to search for disease biomarkers, however the large dynamic range of protein abundance in plasma presents a substantial analytical challenge. Removal of abundant
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