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RAB0857

Sigma-Aldrich

Mouse Ptx3 / Pentraxin-related Protein PTX3 ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.6 ng/mL
standard curve range: 0.614-150 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Ptx3(19288)

General description

The antibody pair provided in this kit recognizes mouse Pentraxin-related Protein PTX3 / Pentraxin 3.
The pentraxin3 (PTX3) gene encodes for a long PTX3 protein, an acute-phase protein. PTX3 protein is a member of the pentraxin family and is present in several cells and tissues. It is observed during brain inflammatory response and seizure. PTX3 plays a role in angiogenesis, tissue remodeling, and female fertility. It promotes phagocytosis of pathogen and inhibits the phagocytosis of apoptotic cells. The antibody pair provided in this kit recognizes mouse pentraxin-related protein PTX3 / pentraxin 3.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Beata Kusnierz-Cabala et al.
Clinical laboratory, 59(9-10), 1003-1008 (2013-11-28)
Pentraxin 3 (PTX3) belongs to the acute phase proteins; its concentration increases significantly in the early stages of inflammation. In nearly 20% of patients with acute pancreatitis (AP) escalated inflammation leads to the development of severe forms of the disease.
Hrishikesh S Kulkarni et al.
JCI insight, 5(17) (2020-08-05)
BACKGROUNDThe complement system plays a key role in host defense but is activated by ischemia/reperfusion injury (IRI). Primary graft dysfunction (PGD) is a form of acute lung injury occurring predominantly due to IRI, which worsens survival after lung transplantation (LTx).
Jingbo Zhang et al.
PloS one, 14(8), e0220772-e0220772 (2019-08-23)
Pentraxin-3 (PTX3) is a multifunctional protein involved in both innate and adaptive immunity. Glucocorticoid (GC) is the first-line therapy to mitigate airway inflammation in asthma. Previous pieces of evidence showed that GC has divergent effects on PTX3 production in various
L Wirestam et al.
Clinical and experimental immunology, 189(1), 83-91 (2017-03-04)
Dysfunctional elimination of cell debris, and the role of opsonins such as pentraxins, is of interest regarding systemic lupus erythematosus (SLE) pathogenesis. Interferon (IFN)-α is typically elevated during SLE flares, and inhibits hepatocyte production of the pentraxin 'C-reactive protein' (CRP)
Masoumeh Moradi et al.
Clinical nutrition (Edinburgh, Scotland), 37(3), 965-969 (2017-05-02)
It has been reported that people may respond differently to the same environmental changes because of genome variations. The main purpose of the present study is to determine gene-diet interactions between -265T>C apolipoprotein A-II polymorphisms and evaluate the effect of weight
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