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C8857

Sigma-Aldrich

ProteoMass Cytochrome c MALDI-MS Standard

vial of 10 nmol, (M+H+) 12,361.96 Da by calculation

Synonym(s):

Cytochrome c from equine heart, Cytochrome c from horse heart

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.24

product line

ProteoMass

Quality Level

form

solid

mol wt

(M+H+) 12,361.96 Da by calculation

packaging

vial of 10 nmol

technique(s)

mass spectrometry (MS): suitable

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

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Application

The specific sites and extent of oxidation in horse cytochrome c treated with H2O2 and UV were characterized. It was suggested that the state of these sites could be used as a biomarker for the oxidative environment in a cell.
Protein calibration standard for MALDI-MS instruments.

Biochem/physiol Actions

Cytochrome c is primarily known as an electron-carrying mitochondrial protein. The transition of cytochrome c between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals. It is generally regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen

Other Notes

Legal Information

ProteoMass is a trademark of Sigma-Aldrich Co. LLC

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Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rawabi Qadhi et al.
Toxicology letters, 219(3), 288-297 (2013-03-26)
The importance of dietary polyunsaturated fatty acids (PUFAs) in the reduction of cardiovascular disease has been recognized for many years. Docosahexaenoic acid (22:6n3, DHA) is an n-3 PUFA known to affect numerous biological functions and provide cardioprotection; however, the exact
Esther Lapuente-Brun et al.
Science (New York, N.Y.), 340(6140), 1567-1570 (2013-07-03)
The textbook description of mitochondrial respiratory complexes (RCs) views them as free-moving entities linked by the mobile carriers coenzyme Q (CoQ) and cytochrome c (cyt c). This model (known as the fluid model) is challenged by the proposal that all
Rebeca Acin-Perez et al.
Biochimica et biophysica acta, 1837(4), 444-450 (2013-12-26)
Mitochondria are important organelles not only as efficient ATP generators but also in controlling and regulating many cellular processes. Mitochondria are dynamic compartments that rearrange under stress response and changes in food availability or oxygen concentrations. The mitochondrial electron transport
Chun Guo et al.
The EMBO journal, 32(11), 1514-1528 (2013-03-26)
Global increases in small ubiquitin-like modifier (SUMO)-2/3 conjugation are a neuroprotective response to severe stress but the mechanisms and specific target proteins that determine cell survival have not been identified. Here, we demonstrate that the SUMO-2/3-specific protease SENP3 is degraded
Keren I Hilgendorf et al.
Genes & development, 27(9), 1003-1015 (2013-04-27)
The retinoblastoma protein gene RB-1 is mutated in one-third of human tumors. Its protein product, pRB (retinoblastoma protein), functions as a transcriptional coregulator in many fundamental cellular processes. Here, we report a nonnuclear role for pRB in apoptosis induction via

Articles

MALDI-TOF MS is a tool for confirming end group identity & transformations, verifying successful & complete conjugation. Functionalized polymers enable a quick & efficient route for synthesis of various polymer conjugates for many applications if apt end group is present.

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