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C0985

Sigma-Aldrich

Cytidine 3′,5′-cyclic mono­phos­phate sodium salt

≥98% (HPLC)

Synonym(s):

cCMP sodium salt

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About This Item

Empirical Formula (Hill Notation):
C9H11N3O7PNa
CAS Number:
Molecular Weight:
327.16
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.77

description

1 vial contains 50μmol or approximately 16mg

Quality Level

Assay

≥98% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O

InChI

1S/C9H12N3O7P.Na/c10-5-1-2-12(9(14)11-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14);/q;+1/p-1/t4-,6-,7-,8-;/m1./s1

InChI key

RZAHVNCNTLFRHJ-IAIGYFSYSA-M

Biochem/physiol Actions

Produced by the hydrolysis of cytidine 5′-triphos­phate by the enzyme cytidylyl cyclase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Newton, R.P.
Nucleosides and Nucleotides, 14, 743-743 (1995)
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Activation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated in vivo by direct binding of the second messenger cAMP. This process plays a fundamental role in the fine-tuning of HCN channel activity and is critical for the modulation of cardiac
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Soluble guanylyl cyclase (sGC) regulates several important physiological processes by converting GTP into the second-messenger cGMP. sGC has several structural and functional properties in common with adenylyl cyclases (ACs). Recently, we reported that membranous ACs and sGC are potently inhibited
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