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C0985

Sigma-Aldrich

Cytidine 3′,5′-cyclic mono­phos­phate sodium salt

≥98% (HPLC)

Synonym(s):

cCMP sodium salt

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About This Item

Empirical Formula (Hill Notation):
C9H11N3O7PNa
CAS Number:
54925-33-6
Molecular Weight:
327.16
EC Number:
259-397-6
MDL number:
MFCD00037485
UNSPSC Code:
41106305
PubChem Substance ID:
329774833
NACRES:
NA.77

description

1 vial contains 50μmol or approximately 16mg

Quality Level

200

Assay

≥98% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O

InChI

1S/C9H12N3O7P.Na/c10-5-1-2-12(9(14)11-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14);/q;+1/p-1/t4-,6-,7-,8-;/m1./s1

InChI key

RZAHVNCNTLFRHJ-IAIGYFSYSA-M

Biochem/physiol Actions

Produced by the hydrolysis of cytidine 5′-triphos­phate by the enzyme cytidylyl cyclase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Newton, R.P.
Nucleosides and Nucleotides, 14, 743-743 (1995)
Kerstin Y Beste et al.
Biochemistry, 51(1), 194-204 (2011-11-30)
Soluble guanylyl cyclase (sGC) regulates several important physiological processes by converting GTP into the second-messenger cGMP. sGC has several structural and functional properties in common with adenylyl cyclases (ACs). Recently, we reported that membranous ACs and sGC are potently inhibited
Todd Michael Seib et al.
Glia, 59(10), 1387-1401 (2011-05-19)
The system x(C)- (Sx(C)-) transporter functions to mediate the exchange of extracellular cystine (L-Cys(2)) and intracellular glutamate (L-Glu). Internalized L-Cys(2) serves as a rate-limiting precursor for the biosynthesis of glutathione (GSH), while the externalized L-Glu can contribute to either excitatory
Toshiaki Kume et al.
Neuroscience letters, 443(3), 199-203 (2008-08-12)
Dibutyryl cyclic AMP (dbcAMP) and retinoic acid (RA) have been demonstrated to be the inducers of morphological differentiation in SH-SY5Y cells, a human catecholaminergic neuroblastoma cell line. However, it remains unclear whether morphologically differentiated SH-SY5Y cells by these compounds acquire
Chika Funaki et al.
Investigative ophthalmology & visual science, 51(12), 6321-6328 (2010-07-31)
The lacrimal gland is primarily responsible for the aqueous portion of the tear film. Simultaneous addition of cholinergic agonists or growth factors with cAMP-dependent agonists potentiates secretion. Recent investigations revealed that cAMP decreases p44/p42 mitogen-activated protein kinase (MAPK) activity stimulated
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