890717O
Avanti
14:1 EPC (Tf Salt)
Avanti Research™ - A Croda Brand 890717O
Synonym(s):
1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (Tf salt)
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About This Item
Empirical Formula (Hill Notation):
C39H73F3NO11PS
CAS Number:
Molecular Weight:
852.03
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
form
liquid
packaging
pkg of 1 × 10 mg (890717O-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 890717O
lipid type
transfection
cationic lipids
shipped in
dry ice
storage temp.
−20°C
General description
Ethylphosphocholine (EPC) are amphiphilic cationic lipids containing hydrophilic headgroup and lipophilic tail.
Biochem/physiol Actions
1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (14:1 EPC) is less toxic and is biodegradable. It is known to possess efficient DNA transfection activity. 14:1 EPC is very closely identical to the natural triacylglyceride lipids.
Packaging
5 mL Clear Glass Sealed Ampule (890717O-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Certificates of Analysis (COA)
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Mikhail A Galkin et al.
Journal of visualized experiments : JoVE, (134) (2018-04-24)
Detergents are indispensable for delivery of membrane proteins into 30-100 nm small unilamellar vesicles, while more complex, larger model lipid bilayers are less compatible with detergents. Here we describe a strategy for bypassing this fundamental limitation using fusogenic oppositely charged
Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery.
Jinjun Shi et al.
Angewandte Chemie (International ed. in English), 50(31), 7027-7031 (2011-06-24)
Rumiana Koynova et al.
The journal of physical chemistry. B, 111(27), 7786-7795 (2007-06-19)
Some mixtures of two cationic lipids including phospholipid compounds (O-ethylphosphatidylcholines) as well as common, commercially available cationic lipids, such as dimethylammonium bromides and trimethylammonium propanes, deliver therapeutic DNA considerably more efficiently than do the separate molecules. In an effort to
Rumiana Koynova et al.
Molecular pharmaceutics, 6(3), 951-958 (2009-04-04)
Synthetic cationic lipids are widely used components of nonviral gene carriers, and the factors regulating their transfection efficiency are the subject of considerable interest. In view of the important role that electrostatic interactions with the polyanionic nucleic acids play in
Rumiana Koynova et al.
Biochimica et biophysica acta, 1768(2), 375-386 (2006-12-13)
Lipoplexes containing a mixture of cationic phospholipids dioleoylethylphosphatidylcholine (EDOPC) and dilauroylethylphosphatidylcholine (EDLPC) are known to be far more efficient agents in transfection of cultured primary endothelial cells than are lipoplexes containing either lipid alone. The large magnitude of the synergy
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