Skip to Content
Merck
All Photos(1)

Documents

264431

Sigma-Aldrich

2,6-Difluorobenzyl bromide

97%

Synonym(s):

α-Bromo-2,6-difluorotoluene

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
F2C6H3CH2Br
CAS Number:
85118-00-9
Molecular Weight:
207.02
Beilstein:
2083943
EC Number:
285-652-6
MDL number:
MFCD00000329
UNSPSC Code:
12352100
PubChem Substance ID:
24856016
NACRES:
NA.22

Quality Level

200

Assay

97%

form

solid

mp

52-55 °C (lit.)

SMILES string

Fc1cccc(F)c1CBr

InChI

1S/C7H5BrF2/c8-4-5-6(9)2-1-3-7(5)10/h1-3H,4H2

InChI key

LSXJPJGBWSZHTM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

2,6-Difluorobenzyl bromide has been used:
  • as reagent in alkylation of the quinazoline-2-thioxo-4-one
  • in the synthesis of 1,3,5-triazine-2,4,6-triones
  • in the preparation of new classes of inhibitors of bovine viral diarrhea virus (as a surrogate virus for hepatitis C virus)

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

4-Bromobenzyl bromide 98%

Sigma-Aldrich

112186

4-Bromobenzyl bromide

Benzyl bromide reagent grade, 98%

Sigma-Aldrich

B17905

Benzyl bromide

Efficient solid-phase synthesis of quinazoline-2-thioxo-4-ones with SynPhase? lanterns.
Makino S, et al.
Tetrahedron Letters, 41(43), 8333-8337 (2000)
Gerhard Puerstinger et al.
Bioorganic & medicinal chemistry letters, 16(20), 5345-5349 (2006-08-12)
A novel class of inhibitors of pestiviruses (5-substituted 2-phenyl-5H-imidazo[4,5-c]pyridines) is described. Modification of the substituent in position 5 resulted in analogues with high activity (EC(50)<100nM) and selectivity (SI>1000) against the pestivirus BVDV (bovine viral diarrhea virus).
Zhiqiang Guo et al.
Bioorganic & medicinal chemistry letters, 15(3), 693-698 (2005-01-25)
A convenient one-pot synthetic route was developed for the preparation of asymmetric 1,3-dialkyl-1,3,5-triazine-2,4,6-triones from readily available alkyl- or aryl-isocyanates, primary amines and N-chlorocarbonyl isocyanate in excellent yields. Subsequent alkylation with N-protected amino alcohols afforded the desired 1,3,5-triazine-2,4,6-triones in good yields.
Gwang-Noh Ahn et al.
Lab on a chip, 19(20), 3535-3542 (2019-09-27)
Microreactors are emerging as an efficient, sustainable synthetic tool compared to conventional batch reactors. Here, we present a new numbering-up metal microreactor by integrating a flow distributor and a copper catalytic module for high productivity of a commercial synthetic drug.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service