1643496

Terbinafine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): trans-N-(6,6-Dimethyl-2-hepten-4-ylyl)-N-methyl-1-naphthylmethylamine hydrochloride
• Empirical Formula (Hill Notation): C₂₁H₂₅N · HCl
• CAS Number: 78628-80-5
• Molecular Weight: 327.89
• NACRES: NA.24
• PubChem Substance ID: 329751232
• UNSPSC Code: 41116107
• MDL number: MFCD00145430

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: terbinafine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• storage temp.: 15-25°C
• SMILES string: Cl[H].[H]\C(CN(C)Cc1cccc2ccccc12)=C(\[H])C#CC(C)(C)C
• InChI: 1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
• InChI key: BWMISRWJRUSYEX-SZKNIZGXSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Allylamine derivative.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Terbinafine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Terbinafine Compounded Oral Suspension
• Terbinafine Hydrochloride
• Terbinafine Tablets

Biochem/physiol Actions

Mode of Action: Inhibits squalene epoxidase, preventing biosynthesis of ergosterol.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Codes: H315,H319,H335,H410
• Precautionary Statements: P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable