T5771

Testosterone 3-(O-carboxymethyl)oxime: BSA - fluorescein isothiocyanate conjugate

• MDL number: MFCD00132415
• UNSPSC Code: 51111800
• NACRES: NA.77

Properties

• Assay: ≥98.00% (TLC)
• Quality Level: 200
• form: powder
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• extent of labeling: ~3 mol FITC per mol BSA; ~10 mol steroid per mol BSA
• technique(s): flow cytometry: suitable
• solubility: water: 1.90-2.10 mg/mL, clear to faintly hazy, orange
• shipped in: ambient
• storage temp.: 2-8°C

Description

Application

Testosterone 3-(O-carboxymethyl)oxime: BSA-FITC has been used for flow cytometric assays in serum-free cell cultures². It has also been used for fluorescence labeling experiments in L6 cells³.

Biochem/physiol Actions

Studies have reported that BSA-coupled testosterone can block the growth of LNCaP cells. Furthermore, it can activate Fas protein and cell death, as well as reduce the translocation, adhesion and incursion of iAR-negative, DU145 prostate cancer cells².

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332,H351
• Precautionary Statements: P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves