B134

BMY 7378 dihydrochloride

≥98% (HPLC), solid

• Synonym(s): 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride
• Empirical Formula (Hill Notation): C₂₂H₃₁N₃O₃ · 2HCl
• CAS Number: 21102-95-4
• Molecular Weight: 458.42
• NACRES: NA.77
• PubChem Substance ID: 24278080
• UNSPSC Code: 12352200
• MDL number: MFCD00153771
• Assay: ≥98% (HPLC)
• Form: solid

Properties

• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: H₂O: >5 mg/mL
• SMILES string: Cl.Cl.COc1ccccc1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O
• InChI: 1S/C22H31N3O3.2ClH/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22;;/h2-3,6-7H,4-5,8-17H2,1H3;2*1H
• InChI key: NIBOMXUDFLRHRV-UHFFFAOYSA-N
• Gene Information: human ... ADRA1D(146), HTR1A(3350)

Description

Biochem/physiol Actions

BMY 7378 dihydrochloride is a partial 5-HT_1A serotonin receptor agonist and selective α_1D-adrenoceptor antagonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Manufactured and sold with the permission of Bristol Myers Squibb Corporation.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)