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Key Documents

A0879

Sigma-Aldrich

N-(4-Aminobenzoyl)-L-glutamic acid

≥98% (TLC)

Synonym(s):

N-(p-Aminobenzoyl)glutamic acid

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About This Item

Empirical Formula (Hill Notation):
C12H14N2O5
CAS Number:
Molecular Weight:
266.25
Beilstein:
2816320
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
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Product Name

N-(4-Aminobenzoyl)-L-glutamic acid, ≥98% (TLC)

Assay

≥98% (TLC)

form

powder

color

off-white to beige

mp

175 °C (dec.)

application(s)

detection
peptide synthesis

storage temp.

−20°C

SMILES string

Nc1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1

InChI key

GADGMZDHLQLZRI-VIFPVBQESA-N

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Application

N-(4-Aminobenzoyl)-L-glutamic acid (ABG) is used as a strong UV absorbing tag for the derivitization of oligosaccharides to enhance their detection in analytical methods such as capillary zone electrophoresis (CZE).

Biochem/physiol Actions

N-p-Aminobenzoyl)-L-glutamic acid is a folate catabolite that can be metabolized by bacterial p-aminobenzoate auxotrophs possessing the enzyme p-aminobenzoyl-glutamate hydrolase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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J Plocek et al.
Journal of chromatography. A, 757(1-2), 215-223 (1997-01-03)
A charged and strongly UV-absorbing tag, N-(4-aminobenzoyl)-L-glutamic acid) (ABG), was coupled to oligosaccharides by reductive amination under mild conditions. The effectiveness of ABG as a derivatization agent is shown through the separation of isomaltooligosaccharides from a dextran hydrolysate. The minimum
SreeDivya Saladi et al.
Molecular cell, 77(1), 189-202 (2019-11-02)
The proteolytic turnover of mitochondrial proteins is poorly understood. Here, we used a combination of dynamic isotope labeling and mass spectrometry to gain a global overview of mitochondrial protein turnover in yeast cells. Intriguingly, we found an exceptionally high turnover
J R Higgins et al.
BJOG : an international journal of obstetrics and gynaecology, 107(9), 1149-1154 (2000-09-26)
To estimate the rate of folate catabolism in pregnant and nonpregnant women and to derive the recommended dietary allowance for folate. Prospective, observational study. Rotunda Hospital, Dublin. WOMEN: Twenty-four healthy gravid women were studied once during each trimester and postpartum.
J F Gregory et al.
The Journal of nutrition, 131(7), 1928-1937 (2001-07-04)
To investigate the effects of pregnancy on folate metabolism, we conducted an 84-d study in second-trimester (gestational wk 14-25) pregnant women (n = 6) and nonpregnant controls (n = 6) with stable-isotopic tracer methods. All subjects were fed a diet
Rita Hannisdal et al.
The Journal of nutrition, 139(7), 1415-1418 (2009-05-22)
Folate is not stable in serum and plasma. This may impair laboratory diagnostics and distort the outcome of epidemiological studies on folate and chronic diseases. The present study was designed to determine the kinetics of folate loss in human serum

Questions

  1. How can I get the expiry date/ retest date of lot # BCBV6788 pertaining to A0879-5G? It is not mentioned in the container or in the Certificate of analysis.

    1 answer
    1. This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

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